Protein Alignment Sec10 and sec-10

DIOPT Version :10

• Sequence 1: NP_651218.1
• Gene: Sec10 / 42863
• FlyBaseID: FBgn0266673
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_501283.2
• Gene: sec-10 / 177562
• WormBaseID: WBGene00016376
• Length: 704
• Species: Caenorhabditis elegans
• Alignment Length: 704
• Identity: 252/704 - (35%)
• Similarity: 403/704 - (57%)
• Gaps: 18/704 - (2%)

  Fly     5 YMEEFEQEPFEVGEFIERLTWRTNNELQNSEDFHPVALHDTFIQTIKDLKILQEKQQSKCERLEE 69
            |:::.|||||:..:.:|:|.||.....|...|  ||:|...|.:.|..|::|.::.|:|...||:
 Worm     9 YVQDLEQEPFDAIDLVEKLAWRMTGSAQTIND--PVSLKMRFEEEIGSLQMLCDQFQNKINTLEK 71

  Fly    70 SLRQEKESHAKKIAKLQERHQTAIDVFGQLDEKINSVAGKIMHLGEQLENVNTPRSRSVEAQKLL 134
            .:.:||:.:.:|:.:|.|::..|||...|||..:.:|:.|::|||:|||:|:.||||:.:|.:|:
 Worm    72 QMNEEKKDYVQKLHRLHEKNGEAIDKMKQLDHTMQAVSTKVVHLGDQLESVDQPRSRAHDAHQLM 136

  Fly   135 NFMSEFLAAGPVIVNDIFADAARLSEAADVIQKLYAISQDLPPGNFAESKRKIEKKYDEVERRLI 199
            ....|||:..| :.:.||.|..:|.|:||::.|||:|||:|....||..:.:|.::|..||..||
 Worm   137 QHFDEFLSDQP-LNSMIFTDPDKLLESADLVHKLYSISQELNKDKFANVQARIGQRYKVVEDLLI 200

  Fly   200 EEFATAQKSEDIERMKTLAQILSQFKGYTQCVDAYIE---QSQMQPYSGKDIFIGIVPLCKHHYE 261
            |||..:|:.|  ::|..:|:|||:||||:.|||.|::   ||......|.:|....:.||:....
 Worm   201 EEFVRSQRDE--KKMAEVAKILSEFKGYSGCVDRYVDFLCQSIHPRGDGGEILADCLQLCRTQQP 263

  Fly   262 IIQKVFANPQQVMSKFILNIYQLKLHQYAMTKL---EDKKDEEKYLRTLYELYSRTLKLSTDLQI 323
            .|..:|.:|..||.|.:|||:..::.:....:|   :|..|:|.|||.|..|||.|||:..:|:.
 Worm   264 RISAIFPSPHTVMQKLVLNIFTGRMKETITARLRECKDTDDQEHYLRDLAYLYSSTLKMCKELEK 328

  Fly   324 YMSTIDDDLLQKLTQQIFIKHLAGYAEMETKCLTAKCSTELEKFYASKKHQKTATTKGFRRNMEV 388
            ...:.|...|..||..||.:::|.|...|.|.|..:||..|::||.||||.|.....|.......
 Worm   329 LHISPDSAFLSTLTDSIFQRYIATYCSEELKYLNDQCSNLLQRFYESKKHVKKQIGGGLHELKRD 393

  Fly   389 LIATRANINIAAIEDYGGETFLSEELAINMLQEAKASLKRCRLLSNETELPGNAIKLNDILLRFL 453
            :.|...|     :|.||||||::|::||::|||.|.:..|...|.::.|||.:...:.|:||::|
 Worm   394 VAARLMN-----VETYGGETFVAEDVAISILQETKNAFGRANQLCDKEELPRHVENIVDVLLKYL 453

  Fly   454 MHEHVDYALELGLQAVPLAEGRVFPQLYFFDVVQKTNIIVHLLDKLCHTSVIPCVSNTPKYSDYV 518
            ..||:|||:|.||..:.|||.:..|..|||.||.|...::.|:.|.....:.|.:..|.......
 Worm   454 YGEHLDYAVETGLAGISLAESKTEPPAYFFSVVAKCTSVILLMIKQFEDPIFPIIKETIVEPSVA 518

  Fly   519 FKKRILMEQIETKLDQGLDRSISAVIGWVKVYLQYEQKKTDYKPET-DVDTISSAACLQVVQNLQ 582
            .|.:..:..:|:|:..||:|.:::::|:|| :|..||||||::|:: .:|...|..|....:.|.
 Worm   519 KKWQQSLRSLESKMSLGLERQLNSIVGYVK-FLFSEQKKTDFRPDSQQIDIRVSPQCQLASRFLA 582

  Fly   583 PVIVQIKKCVDGENLQNVLTEFGTRLHRVIYDHLQTMQFNTAGAMCAICDVNEYRKCIRELDSPL 647
            ..:..::...|||||:.:.::..|||.:.:..|:|...:|:.||:..:|||.|.|..:.:.....
 Worm   583 NQVAAMELGCDGENLEALQSDLATRLFKFMLTHIQQFTYNSTGAVLLLCDVGELRTLVSKWRVQN 647

  Fly   648 VTQLFDILHALCNLLLVKPQNLQEVCTGDTLNYLDKSVVRQFIQLRTDFRIIKN 701
            ....::.|.||.|||.|.|..:.|......|..:|:.::..|::||||||.|||
 Worm   648 ALTQWESLQALTNLLAVLPDQVNETAHSSLLENVDRQLIHDFVRLRTDFRSIKN 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec10	NP_651218.1	Sec10	89..705	CDD:399988	224/620 (36%)
sec-10	NP_501283.2	Sec10	91..703	CDD:399988	224/620 (36%)