Protein Alignment Root and crocc

DIOPT Version :9

• Sequence 1: NP_001287497.1
• Gene: Root / 42860
• FlyBaseID: FBgn0039152
• Length: 2048
• Species: Drosophila melanogaster
• Sequence 2: XP_031762449.1
• Gene: crocc / 100486658
• XenbaseID: XB-GENE-996807
• Length: 2037
• Species: Xenopus tropicalis
• Alignment Length: 2015
• Identity: 575/2015 - (28%)
• Similarity: 1035/2015 - (51%)
• Gaps: 220/2015 - (10%)

  Fly    90 ALLRQNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETIKP 154
            :|.:||.|||:||.:|..:|:|:|..|::.|..||.||.:||:|:.||:::|.:.|:::.|  :.
 Frog   126 SLAQQNVELRRRLEEEQAAYKRKLQAYQEGQQRQAQLVQKLQAKVMQYKKKCGEAEQQLLE--RS 188

  Fly   155 TAGVGPKLTTGPTNQVLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVLVTGGGAGAAELCRK 219
            |.....:||:.     |..|...|.|.             ..:.:.::|.|:            :
 Frog   189 TELEQERLTSR-----LELTDTRLRQE-------------EAANNDLEDALI------------R 223

  Fly   220 LEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFK 284
            ||||.||...:...|:.||:||:::|..|:||:.||:|||.||...|:||..:|.|::.||::|.
 Frog   224 LEEEQQRSTSLAQVNAMLREQLDQANSANQALSEDLRKLTADWTKAREELEQRESEWRREEESFN 288

  Fly   285 DYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEI---------NCVGKDINGSNATV 340
            .|:::||:|||.:||:||:::|.|.||::..:.:::::.:|:         :|:  :::||....
 Frog   289 SYFSNEHSRLLSLWRQVVSLRRLFSEMKSMTERDLSQLHKELSQSCRSLHASCL--NVSGSQRMA 351

  Fly   341 -AFAVQQAKRAA------DDELKQSQRSNDELQNQLATLKVQYESARHEIMERDQRLLELMNQLK 398
             :..|.||:|.|      :::||...|       |:..|:..|::.:.|:   :.::.||....:
 Frog   352 ESTGVVQAERQALQLAQLEEQLKDKVR-------QMIQLQAAYDAEKAEL---NAKVTELNKTAE 406

  Fly   399 KLEDRC-------------AQAESQAALASRYSD----EIERLNNSMREIAQAVVQDAEN----- 441
            :|:|..             :::|.||||.....|    |.|.|..::||:.|||:.|:::
 Frog   407 RLQDESRESERQRLQEQEQSRSEEQAALLGEEVDALKCEKEVLQEALRELTQAVLSDSDSGLQLS 471

  Fly   442 -ADREADAEVTGGVMQHMHLTRDAASVVGGAGGAGSTAGG-GGKSPRRNST---RASQAFAEGTI 501
             :||.:|...:.|:         ..|:.||...:..|:.. ...||.|:|:   ..|.||.|..:
 Frog   472 GSDRTSDPTESEGL---------GFSLRGGLSSSLRTSSPLRRSSPHRSSSPRRSLSPAFRESAV 527

  Fly   502 SAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSE 566
            |||.:||.:.||.|.:::.:.....||:.:.:.||..:|..::.|..|:|||.::.|.......:
 Frog   528 SAVHSALQRRQLQLQELRGRLDAGQETVGSLRKQLSDNENERRALEQKIQQLQQERDVMGGAKED 592

  Fly   567 LLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVE 631
            ..::...|:..::.:..:|...|....::.........:.||:||....||::.|.::|:|:.|.
 Frog   593 AERDVTRLRNHIEQLNGEKGALEKSLQNLQEELNGQRQENEKLQLANSDLQRQRDLLQEEKEDVC 657

  Fly   632 LEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQ 696
            .:.:|.|::.:.........|.:.|.||:|.:.::|.|::.||.|::.|.:|::....::..|.:
 Frog   658 RDRERALQNVDRGHKAQEQLEVKLSALRKELVVVKESLHKCSLEREVSEAERVDVSQALSKAETR 722

  Fly   697 KSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIG 761
            .::||..|::...|:..|::...|:|..:.|.:.:...:...:.:.:|||..|:.|..:...|..
 Frog   723 LAELELTLNRQRTEEASLRDALSKMSALNESLAQDKTELSRIIAQLEEERAHLQGQKHEVEQEKA 787

  Fly   762 ELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEAL 826
            .::.||..|::.:|||:|:.......|:.::..:||:||::..:.::||.:..||..:.|::..|
 Frog   788 SIRDELVRLEQEKLELDTERFGLDNSLQAMEQNREKLLQEVQALRKERGQLQEQLGQVSRQRNML 852

  Fly   827 NEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLES 891
            :|:|:::|:.:|..:|...|.:|..||::||.....|.:...|:::..|.|.:|.||:|||:||:
 Frog   853 SEDLVQSRRDVELQSECLLRASREKEELMKDKGSLVVQLTASERESRALAEEIAVLRTEKEALET 917

  Fly   892 VLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAA 956
            .||:....|.....|:.|||.:.|...:.:|||:..:..:::::|....|.:..|..|.......
 Frog   918 ALFEAQQQLIHVTSRKEQLEVESQNLRLNKESLQGEIGSVRRQMEAEISKLERDKEALSQQLNQM 982

  Fly   957 ESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDD-------EIEKLQER 1014
            |.:....:.|.|....|..:|..:|..:||..||...::.:..|...:::       |.|::.|.
 Frog   983 EQEAQVTLRNEQRAHGEDVERLSQEKNELRLELESEKEELVHRLTQEREELVARHEMEREEMSEE 1047

  Fly  1015 LATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREA 1079
            :|.||       |:.:|:|::||.||||||.:...:|.:::|||......|......|:|.:|::
 Frog  1048 IAALQ-------QERDESLLQAEFEKQQALSVKESEKASLSERLTQAQHGLSGLSLELERHKRDS 1105

  Fly  1080 NARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREE-------RESLCRVSE 1137
            ..|.|:.|..|..|..|:..:|.       :|||.:...:.:|..|.|:       |||..|..|
 Frog  1106 QIRQEQDRGTILALNSELKGLRG-------QLEEALVLHDRELKGLNEKSREVSKHRESAQREVE 1163

  Fly  1138 ELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKEL 1202
            |||.::.:.||..::...||.:|.|:.:||:..::..:||..:.||.|.|...|::....||:||
 Frog  1164 ELKTQLCVVEDARDAVRRELIEAHRRVREGQELLEGHKKENMELRRALGDEAKEKEAVQKSNEEL 1228

  Fly  1203 RDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKA 1267
            |..|:|.||.:....|:.||..|::|.||:.:.:.|.|...|.:.|::.|....:..::|...:.
 Frog  1229 RGAVRRAESERISLKRSNEEKEQRLSVLEEARGASEKEVNDLRSSLRDVERSRLEARRELQDLRR 1293

  Fly  1268 QLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQN 1332
            ||:....|..::.....|:|.:|....:.:|.::::...:|::|.:.||...|.|:||...:.:.
 Frog  1294 QLKLLDDESIKRSRDMAEVQARLSTYEQREEESRRDNFNLKQKLMETEAGREAARKELSALQRKV 1358

  Fly  1333 NQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDE 1397
            .:.|..|..||:||...|:|.||.||:|.|...|||:.|..|.::..:|..||..:|||:..|:.
 Frog  1359 AEVEGEFGVRERELQGSLDEARGNEKKLLDNTRNLEIKLQAAQEESGQLGLRLSASEGRVHGLEA 1423

  Fly  1398 QLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDG---SVNLSHRLLSPSRRFSPSRSCGDYDNR-- 1457
            :||.:|..||:.|.||.|:...|||..||...|   |.....|..||.|||||.::   :||.
 Frog  1424 ELSRLEGLKREVEFKLGSLHSALRRTLGIGRAGRTPSPAYRGRSGSPKRRFSPLKA---FDNTFA 1485

  Fly  1458 ----------------STSQCPDGPI----------DVDPDLVRKGVRNLMHQVAQLEREKDDYK 1496
                            ..|:.|:.|:          |:||::||..:|:.:.::...|||:|:.:
 Frog  1486 TTTDGRGSPIPRTGSPDRSKTPERPLSPTRGEQLVADIDPEVVRAALRDFLQELRDTERERDELR 1550

  Fly  1497 SQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQAL----EEKLKH 1557
            :|||.:.:.|.:...::.....::.:||.:|...:|.|.|::.    |:..:|..    ||.|:.
 Frog  1551 TQLGTSNRHLAEMEAERDGALTRVQQLQKVLSECEEAKRNVDG----KLGGLQTTLILQEETLRR 1611

  Fly  1558 RNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLE 1622
            ...|.::.:|:.|..|..|.|...|....::::.|.:...:|.:||:|:|:|.|...|.|.:|||
 Frog  1612 YERERKLAQEKAASLERSLQAAEGEQRAAQDKMNKIKANEAKYENERRRLKEVLDASESRNTKLE 1676

  Fly  1623 LQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVS 1687
            |.|..:||:|.|.::.|.:::..:::|.:|:|...|.|:..|.|...|:..|::|...|.|:..|
 Frog  1677 LSRRGLEGELQRHKLVLADREAEMQEMQQRMEALQRQLSDSEGRVGTLQLCVERLNSTLAKAQES 1741

  Fly  1688 ETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQ 1752
            ||.|:.::::|...||:....|.::.|||..:||.|..:|:|:|||.|||::|:..:.|.::...
 Frog  1742 ETSLKEKVQSLTGALSDSNCTSASSHDKLNQLQKVLTGSEHERRILQERLEAARQAVAEGKKQNV 1806

  Fly  1753 AQLDGNQRLQEQVTDLEVQRSALESQLR----IAKWNQESGGDKDLTNGNGGGNGEEELSRQLKS 1813
            |.::.||.|:::..:.|:||:.||.|:|    |.:..|||.|..               .|.::.
 Frog  1807 ALMEQNQVLRDEQAEGELQRAELEGQVRQMQEILRQRQESEGAS---------------LRNVQK 1856

  Fly  1814 SQREKSELRSKLQTLQDKVKQLECDR-----------KSKFSGGNAYDRAEKSNSFYGGAAESGE 1867
            .|.|:..|:.:|..||..|.|||.::           |.|.:.....|:.|:..      .::.|
 Frog  1857 LQEEREVLQERLCGLQRAVVQLESEKREVERSSMRLEKDKNALKKTLDKVEREK------LKTAE 1915

  Fly  1868 FDSNRYDVGGGNAGGGSFNCGLDHSV--IEQETRDLRLKVRRLETLLAEKESELARCKARMNDSA 1930
             |:.|.....|.         ||.|:  :|||..:.:.:|:.||..:|:.|...::   .:.::|
 Frog  1916 -DTLRLSAEKGR---------LDRSLTTVEQELAEAQRQVQLLEAQMADMEQTHSQ---SLMETA 1967

  Fly  1931 KCHD---GLDGDRYRSAQMHAEKLLDAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSS 1992
            ..|.   .|:.:|.|:||:.||:.|||||::|||::..||.|||.|::||.||.:|.|:...:.|
 Frog  1968 TRHRQELQLEIERLRNAQIQAERTLDARERAHRQRIRGLEEQISTLKDQLQQELRRCQKVFSQPS 2032

  Fly  1993  1992
             Frog  2033  2032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Root	NP_001287497.1	Rootletin	110..332	CDD:291694	71/230 (31%)
		Smc	555..1384	CDD:224117	228/842 (27%)
		SMC_prok_B	991..>1779	CDD:274008	251/836 (30%)
crocc	XP_031762449.1	Rootletin	146..336	CDD:405685	70/221 (32%)
		SMC_prok_B	539..1360	CDD:274008	220/834 (26%)
		Smc	1097..1919	CDD:224117	252/857 (29%)
		COG4372	1857..>2034	CDD:226809	59/195 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	659	1.000	Domainoid score	I153
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	797	1.000	Inparanoid score	I493
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D48753at33208
OrthoFinder	1	1.000	-	-		FOG0001653
OrthoInspector	1	1.000	-	-		otm48101
Panther	1	1.100	-	-	LDO	PTHR23159
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3005
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160