Sequence 1: | NP_001341533.1 | Gene: | MITF / 4286 | HGNCID: | 7105 | Length: | 526 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_572167.3 | Gene: | Usf / 31384 | FlyBaseID: | FBgn0029711 | Length: | 437 | Species: | Drosophila melanogaster |
Alignment Length: | 389 | Identity: | 76/389 - (19%) |
---|---|---|---|
Similarity: | 131/389 - (33%) | Gaps: | 105/389 - (26%) |
- Green bases have known domain annotations that are detailed below.
Human 93 SQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTT---LANKHANQ 154
Human 155 VLSLPCPNQPGD-----HVMPPVPGS------------SAPNSPMAMLTLNSNCEKEGFYKFEEQ 202
Human 203 NRAESECPGMNTHSRASC-MQMDDVID----DIISLESSYNEEILGLMDPALQMANTLPVSGNLI 262
Human 263 D-------------LYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARALAKER--QK 312
Human 313 KDNHNLIERRRRFNINDRIKELGTLIPK----------SNDPDMRW------------------- 348
Human 349 ------NKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQEL----EMQARAH 402 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
MITF | NP_001341533.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..54 | ||
MITF_TFEB_C_3_N | 56..194 | CDD:318217 | 25/120 (21%) | ||
Transactivation | 224..295 | 14/87 (16%) | |||
HLH | 309..369 | CDD:238036 | 22/96 (23%) | ||
Leucine-zipper. /evidence=ECO:0000305|PubMed:24631970 | 374..395 | 3/20 (15%) | |||
DUF3371 | 397..516 | CDD:314681 | 3/6 (50%) | ||
DNA binding regulation | 401..431 | 1/2 (50%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..526 | ||||
Usf | NP_572167.3 | HLH | 255..343 | CDD:278439 | 19/87 (22%) |
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1318 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1708 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.840 |