DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13605 and amfra

DIOPT Version :9

Sequence 1:	NP_651214.2	Gene:	CG13605 / 42858	FlyBaseID:	FBgn0039150	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_998328.2	Gene:	amfra / 406442	ZFINID:	ZDB-GENE-040426-2190	Length:	620	Species:	Danio rerio

Alignment Length:	168	Identity:	39/168 - (23%)
Similarity:	71/168 - (42%)	Gaps:	43/168 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 YIAVSDLIIKLLTMLVKLIITMLPHHLMRLKVRARLYVLVEYISQFYRAMTPITQWLLF--LYES 550
            ||..:|.|::|..:.:.|:     ||:                           ..|||  ::.|
Zfish   249 YIYYTDFIMELAILSLDLM-----HHI---------------------------HMLLFGNIWLS 281

  Fly   551 YSGLEVVSGGLFSAMYLGAKIFELVERGKSLKKAIVTFRKNIDSE-RPPTKDELDAAGALCPICH 614
            .:.|.:    .....:|..::...:.|.|:..:.|    .|::|. ...|.:||.|....|.||.
Zfish   282 MASLVI----FMQLRHLFHEVQRRIRRHKNYLRVI----DNMESRFAVATPEELAANNDDCAICW 338

  Fly   615 DAFNTPTVLECGHIFCDECVQTWFKREQTCPMCRAKVS 652
            |:..|...|.|||:|.:.|:::|.:::.:||.||..::
Zfish   339 DSMTTARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLN 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13605	NP_651214.2	RING	610..651	CDD:238093	16/40 (40%)
amfra	NP_998328.2	zf-rbx1	79..>375	CDD:331150	39/165 (24%)
		RING-H2_AMFR	332..375	CDD:319369	16/42 (38%)
		RING-H2 finger (C3H2C3-type)	334..371	CDD:319369	14/36 (39%)
		CUE_AMFR	451..491	CDD:270604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820