DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13605 and rnf-145

DIOPT Version :9

Sequence 1:	NP_651214.2	Gene:	CG13605 / 42858	FlyBaseID:	FBgn0039150	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_491382.2	Gene:	rnf-145 / 172053	WormBaseID:	WBGene00022471	Length:	742	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	60/324 - (18%)
Similarity:	104/324 - (32%)	Gaps:	106/324 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 LPLIFILFFKFLHDHLLGIVDLLVLQTVMYNVNRSVRNQVARLAQKNYAVMVRDTFLVAVVVTVR 418
            |.|:..:....|...|..|:::::|     |:..|.....||.|:   .:.:....:|....|.:
Worm   397 LALVLYIVISALLQSLFEIIEVVLL-----NLPSSPTASRARHAR---CICIALLLVVIPFFTTK 453

  Fly   419 LFLATSPPDPFGLIVPPSRKS-------VFIEVTALPFHTSSEGDSPTTSSEPIKTNMYKDTYKS 476
            ..||..|.|.:..|:..:..:       |.::...|...|.||        ||.:
Worm   454 TMLALLPIDIYTAIIIANSATVTARAIGVILKYIVLIVETKSE--------EPWE---------- 500

  Fly   477 LNVIPLGMLLYYIAVSDLIIKLLT----------MLVKLIITMLPHHLMRLKVRARLYVLVEYIS 531
                .:..|.|||..::..|:||.          .:||:..:.....::...|...:|..:|:..
Worm   501 ----GIDDLTYYIDCANKGIELLAAKVVMVFGCMQVVKVGFSFATFAILLFHVIVNIYKRLEHTV 561

  Fly   532 QFYRAMTPITQWLLFLYESYSGLEVVSGGLFSAMYLGAKIFELVERGKSLKKA-IVTFRKNIDSE 595
            .|.:...                                  ..|:....|.|| :|..|:..|
Worm   562 SFIKNRN----------------------------------AAVKNINRLSKADVVQLRERED-- 590

  Fly   596 RPPTKDELDAAGALCPIC-----HDAFNTPTVLECGHIFCDECVQTWFKREQTCPMCRAKVSDD 654
                         :|.||     .:|..||    |.|.|...|::.|...:..||:|...:.:|
Worm   591 -------------VCAICFIEMKEEARITP----CKHYFHGPCLRKWLAVKMVCPLCYTYMKED 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13605	NP_651214.2	RING	610..651	CDD:238093	14/45 (31%)
rnf-145	NP_491382.2	TRC8_N	49..556	CDD:372682	36/188 (19%)
rnf-145	NP_491382.2	RING-H2_RNF139_like	590..631	CDD:319390	14/59 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820