DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and Ubqln4

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_277068.1	Gene:	Ubqln4 / 94232	MGIID:	2150152	Length:	596	Species:	Mus musculus

Alignment Length:	291	Identity:	72/291 - (24%)
Similarity:	122/291 - (41%)	Gaps:	64/291 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLSIRMLDQRTITLEMNESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAED 66
            |..|.:.||.::. |..|....|...|:           :.|.||::|:|::|...||::.|.:.
Mouse    23 KEEIVICDQASVK-EFKEEISRRFKAQQ-----------DQLVLIFAGKILKDGDTLSQHGIKDG 75

  Fly    67 ---KIIVLMGKKKVD--------KSSPEEKVAP--TP--PLAA------------------GPNV 98
               .:::...:|..|        .|:|:...||  ||  |.||                  ||:.
Mouse    76 LTVHLVIKTPQKAQDPVTAAASPPSTPDSASAPSTTPASPAAAPVQPCSSGNTTSDAGSGGGPSP 140

  Fly    99 LRTE---DVVPSLAPNDQWVSDLMSMGYGE----EEVRSALRASFNHPERAIEYLINGIPQEVVS 156
            :..|   ....|:......:..|.|:|.|.    |..:...|...::||...:.:.|.:.|:::|
Mouse   141 VAAEGPSSATASILSGFGGILGLGSLGLGSANFMELQQQMQRQLMSNPEMLSQIMENPLVQDMMS 205

  Fly   157 EQGLAAIPSVQTSDQLQQLMADLNITRMREMINQNPELIHRLMNRLAETDPATFEVFQRNQEE-L 220
            ...|.. ..:..:.|:|||| :.| ..:..|:| ||||:.:.| .||. :||..:...|||:. |
Mouse   206 NPDLMR-HMIMANPQMQQLM-ERN-PEISHMLN-NPELMRQTM-ELAR-NPAMMQEMMRNQDRAL 264

  Fly   221 MNM--ISGGAS---RTPNEIEHLQITLTAEE 246
            .|:  :.||.:   |...:|:....|...|:
Mouse   265 SNLESVPGGYNALRRMYTDIQEPMFTAAREQ 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	72/291 (25%)
		UBQ	1..76	CDD:294102	17/76 (22%)
		UBA1_Rad23_like	110..148	CDD:270466	8/41 (20%)
		XPC-binding	172..227	CDD:286376	21/57 (37%)
		UBA2_Rad23_like	245..282	CDD:270467	1/2 (50%)
Ubqln4	NP_277068.1	UBQ	13..83	CDD:214563	17/71 (24%)
		hPLIC_N	13..83	CDD:176403	17/71 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..148		13/58 (22%)
		STI1	187..224	CDD:128966	9/37 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..361
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	482..528
		UBA_PLICs	553..592	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810