DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and DSK2

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_014003.1	Gene:	DSK2 / 855319	SGDID:	S000004889	Length:	373	Species:	Saccharomyces cerevisiae

Alignment Length:	246	Identity:	59/246 - (23%)
Similarity:	95/246 - (38%)	Gaps:	52/246 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EMNESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAEDKIIVLMGKKKVDKS 80
            |:|.:.|...|:.|........:|..|.:|||||:|::|...:..|.|.:...:.|:      ||
Yeast    15 EVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLV------KS 73

  Fly    81 SPEEKVAPTPPLAAGPN------VLRTEDVVPSLAPNDQW----VSDLMSMGY-GEEEVRS---- 130
            .|:.:.|.    |||.|      ........|:::.....    ::||.|..| |...:.|
Yeast    74 QPKPQTAS----AAGANNATATGAAAGTGATPNMSSGQSAGFNPLADLTSARYAGYLNMPSADMF 134

  Fly   131 -----ALRASFNHPERAIEYLINGIPQEVVSEQGLAAIPS-----VQTSDQLQ----QLMADLNI 181
                 ||....|:.:..:..:.|.|.|..::|  :.:.|.     :|::.|||    |....|..
Yeast   135 GPDGGALNNDSNNQDELLRMMENPIFQSQMNE--MLSNPQMLDFMIQSNPQLQAMGPQARQMLQS 197

  Fly   182 TRMREMINQNPELIHRLMNRLAETDPATFEVFQRNQEELMNMISGGASRTP 232
            ...|:|:. ||::|.:.|......||          ...|....|.||..|
Yeast   198 PMFRQMLT-NPDMIRQSMQFARMMDP----------NAGMGSAGGAASAFP 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	59/246 (24%)
		UBQ	1..76	CDD:294102	17/59 (29%)
		UBA1_Rad23_like	110..148	CDD:270466	9/51 (18%)
		XPC-binding	172..227	CDD:286376	13/58 (22%)
		UBA2_Rad23_like	245..282	CDD:270467
DSK2	NP_014003.1	Ubl_Dsk2p_like	3..74	CDD:340523	18/64 (28%)
		STI1	149..185	CDD:128966	7/37 (19%)
		UBA_Dsk2p_like	328..369	CDD:270509
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810