DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and UBI4

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_013061.1	Gene:	UBI4 / 850620	SGDID:	S000003962	Length:	381	Species:	Saccharomyces cerevisiae

Alignment Length:	285	Identity:	55/285 - (19%)
Similarity:	117/285 - (41%)	Gaps:	59/285 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLSIRMLDQRTITLEMNESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAE 65
            |::.::.|..:|||||:..|..:..:|.|:.:  :..:|.:..:||::|:.:||...||:|.|.:
Yeast     1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQD--KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQK 63

  Fly    66 DKII---------------VLMGKK---KVDKSSPEEKVAPTPPLAAGPNVLRTEDVVPSLAPND 112
            :..:               .|.||.   :|:.|...:.|         .:.::.::.:|   |:.
Yeast    64 ESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNV---------KSKIQDKEGIP---PDQ 116

  Fly   113 QWVSDLMSMGYGEEEVRSALRASFNHPERAIEYLI----NGIPQEVVSEQGLAAIPSVQTSDQLQ 173
            |   .|:..|...|:.|:.  :.:|..:.:..:|:    .|:...|.:..|......|::||.:.
Yeast   117 Q---RLIFAGKQLEDGRTL--SDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTID 176

  Fly   174 QLMADLNITRMREMINQNPELIHRLMNRLAET-----DPATFEVFQRNQEELMNMI---SGGASR 230
            .:.:.:          |:.|.|.....||...     |..|...:...:|..::::   .||...
Yeast   177 NVKSKI----------QDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQI 231

  Fly   231 TPNEIEHLQITLTAEETAAVGRLEA 255
            ....:....|||..|.:..:..:::
Yeast   232 FVKTLTGKTITLEVESSDTIDNVKS 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	55/285 (19%)
		UBQ	1..76	CDD:294102	23/92 (25%)
		UBA1_Rad23_like	110..148	CDD:270466	8/41 (20%)
		XPC-binding	172..227	CDD:286376	8/62 (13%)
		UBA2_Rad23_like	245..282	CDD:270467	1/11 (9%)
UBI4	NP_013061.1	Ubl_ubiquitin	1..76	CDD:340501	20/76 (26%)
		Ubl_ubiquitin	77..152	CDD:340501	15/91 (16%)
		Ubl_ubiquitin	153..228	CDD:340501	13/84 (15%)
		Ubl_ubiquitin	229..304	CDD:340501	4/28 (14%)
		Ubl_ubiquitin	305..380	CDD:340501
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900