DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and RAD23A

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_173070.1	Gene:	RAD23A / 838188	AraportID:	AT1G16190	Length:	368	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	92/382 - (24%)
Similarity:	165/382 - (43%)	Gaps:	106/382 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLSIRMLDQRTITLEMNESQEVRALKQKLGNLPEVAMPAENLQ-----LIYSGRIMEDAMPLSE 60
            |||:::.|......:.:..:..:.|:|:.:    |.:...:|..     ||::|::::|...|.|
plant     1 MKLTVKTLKGSHFEIRVLPTDTIMAVKKNI----EDSQSKDNYPCGQQLLIHNGKVLKDETTLVE 61

  Fly    61 YRIAEDK-IIVLMGKKKVDKSSPEEKVAPT---------------------------------PP 91
            .::.|:. ::|::.|.|...|:......||                                 .|
plant    62 NKVTEEGFLVVMLSKSKTASSAGPSSTQPTSTTTSTISSTTLAAPSTTQSIAVPASNSTPVQEQP 126

  Fly    92 LAAGPNVLRTEDVVPSLAPNDQWVSDLMSMGYG---EEEVRSALRASFNHPERAIEYLINGI--- 150
            .|......:....:.|.:..:|.|..:|.||.|   :|.|..||||::|:||||::||.:||
plant   127 TAQSDTYGQAASTLVSGSSIEQMVQQIMEMGGGSWDKETVTRALRAAYNNPERAVDYLYSGIPET 191

  Fly   151 ----------------------------------PQEVVSEQG---LAAIPSVQTSDQLQQLMAD 178
                                              |||.||:..   |..:..::.:||.|||
plant   192 VTIPATNLSGVGSGRELTAPPPSGGPNSSPLDLFPQEAVSDAAGGDLGTLEFLRGNDQFQQL--- 253

  Fly   179 LNITRMREMINQNPELIHRLMNRLAETDPATFEVFQRNQEELMNMI------SGG----ASRTPN 233
                  |.|:|.||:::..::..|.:.:|....:.|.||.|.:.::      |.|    ..:...
plant   254 ------RSMVNSNPQILQPMLQELGKQNPQLLRLIQENQAEFLQLLNEPYEGSDGDVDIFDQPDQ 312

  Fly   234 EIEHLQITLTAEETAAVGRLEALGFERVMAVQAYLACDKDEQLAAEVLIRQSEEDRD 290
            |:.| .:.:|.||..::.||||:||:|.:.::|:|:||::|:|||..|:..|.:..|
plant   313 EMPH-SVNVTPEEQESIERLEAMGFDRAIVIEAFLSCDRNEELAANYLLEHSADFED 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	90/374 (24%)
		UBQ	1..76	CDD:294102	17/80 (21%)
		UBA1_Rad23_like	110..148	CDD:270466	19/40 (48%)
		XPC-binding	172..227	CDD:286376	15/60 (25%)
		UBA2_Rad23_like	245..282	CDD:270467	17/36 (47%)
RAD23A	NP_173070.1	rad23	1..365	CDD:273167	91/377 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	40	1.000	Domainoid score	I4837
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53856
OrthoDB	1	1.010	-	-		D1260050at2759
OrthoFinder	1	1.000	-	-		FOG0001474
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101279
Panther	1	1.100	-	-	O	PTHR10621
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790