DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10694 and UBB

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001268645.1	Gene:	UBB / 7314	HGNCID:	12463	Length:	229	Species:	Homo sapiens

Alignment Length:	192	Identity:	40/192 - (20%)
Similarity:	91/192 - (47%)	Gaps:	23/192 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLSIRMLDQRTITLEMNESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAE 65
            |::.::.|..:|||||:..|..:..:|.|:.:  :..:|.:..:||::|:.:||...||:|.|.:
Human     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQD--KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQK 63

  Fly    66 DKIIVLMGK---------KKVDKSSPEEKVAPTPPLAAGPNVLRTEDVVPSLAPNDQWVSDLMSM 121
            :..:.|:.:         |.:...:...:|.|:..:......::.::.:|   |:.|   .|:..
Human    64 ESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIP---PDQQ---RLIFA 122

  Fly   122 GYGEEEVRSALRASFNHPERAIEYLI----NGIPQEVVSEQGLAAIPSVQTSDQLQQLMADL 179
            |...|:.|:.  :.:|..:.:..:|:    .|:...|.:..|......|:.||.::.:.|.:
Human   123 GKQLEDGRTL--SDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKI 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	40/192 (21%)
		UBQ	1..76	CDD:294102	21/83 (25%)
		UBA1_Rad23_like	110..148	CDD:270466	8/41 (20%)
		XPC-binding	172..227	CDD:286376	1/8 (13%)
		UBA2_Rad23_like	245..282	CDD:270467
UBB	NP_001268645.1	Ubl_ubiquitin	1..76	CDD:340501	21/76 (28%)
		Ubl_ubiquitin	77..152	CDD:340501	12/82 (15%)
		Ubl_ubiquitin	153..228	CDD:340501	6/30 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810