DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and Ubqln5

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_081910.1	Gene:	Ubqln5 / 70980	MGIID:	1918230	Length:	510	Species:	Mus musculus

Alignment Length:	276	Identity:	60/276 - (21%)
Similarity:	114/276 - (41%)	Gaps:	48/276 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAEDKIIVLMGKKKVDKSSPE 83
            |:..||..|:::...  :...|:.|.||::|:|:.|...||:..|.:...:.::.:..:..|
Mouse    41 ENSNVRRFKKQISKY--LHCNADRLVLIFTGKILRDQDILSQRGILDGSTVHVVVRSHLKGS--- 100

  Fly    84 EKVAPTPPLAAGPNVLRTEDVVPS-----LAPNDQWVSDLMSMGYGEEEVRSALRASFNHPERAI 143
               |.|..| .||....|....||     ||.....::|..|     :.|:....|    ||..:
Mouse   101 ---ACTGTL-VGPTGQYTHRSEPSAKLGRLAGTSPDLADFFS-----QRVQLLPAA----PESVV 152

  Fly   144 EYLINGIPQEVVSEQGLAAIPSVQTSDQLQQLMADLNITRMREMINQNPELIHRLMNRLAETDPA 208
            :.|.:.:.|.:.:|:....:...:||..:|:          |:...:.||.:.:         ||
Mouse   153 QLLEDPLIQGLANEKHANGVHIPETSKTVQK----------RDPALKFPETLQK---------PA 198

  Fly   209 -TFEVFQRNQE--ELMNMISGGASR---TPNEIEHLQITLTAEETAAVGRLEALGFERVMAVQAY 267
             :.||.|.:::  |.:..:.||.:.   :.::|..:.::..|...|:.|.:.||...|.....|:
Mouse   199 QSQEVLQEHKQRLEALKAVPGGDNAMHPSCSDIHQVMLSTLALLVASKGHISALELCRGETNNAH 263

  Fly   268 LACDKDEQLAAEVLIR 283
            .:.|.....|...|:|
Mouse   264 SSSDPTTIPATSPLVR 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	60/276 (22%)
		UBQ	1..76	CDD:294102	14/56 (25%)
		UBA1_Rad23_like	110..148	CDD:270466	7/37 (19%)
		XPC-binding	172..227	CDD:286376	10/57 (18%)
		UBA2_Rad23_like	245..282	CDD:270467	8/36 (22%)
Ubqln5	NP_081910.1	UBQ	24..94	CDD:214563	14/54 (26%)
		UBQ	24..94	CDD:294102	14/54 (26%)
		UBA_PLICs	467..506	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810