DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and UBQLN3

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001334025.1	Gene:	UBQLN3 / 50613	HGNCID:	12510	Length:	655	Species:	Homo sapiens

Alignment Length:	225	Identity:	48/225 - (21%)
Similarity:	103/225 - (45%)	Gaps:	37/225 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAEDKIIVLMGKKK---VDKSSPEE 84
            ::.||:::....: |.| :.|.||::|:|::|...|::..:.:...:.|:.|::   :....|..
Human    43 IQQLKEEISQRFK-AHP-DQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKRQHRAMGNECPAA 105

  Fly    85 KV---APTPPLAAGPNVLRTEDVVPSLAPNDQWVSDLMSMGYG----EEEVRSALRASFNHPERA 142
            .|   .|:|.....|:.:...|..|:.:..  .::.|..:|..    .::..|.:|...:.||..
Human   106 SVPTQGPSPGSLPQPSSIYPADGPPAFSLG--LLTGLSRLGLAYRGFPDQPSSLMRQHVSVPEFV 168

  Fly   143 IEYLINGIPQEVVSEQGLAAIPSVQTSDQLQQLMADLNITRMREMINQNPELIHRLMNR--LAET 205
            .:.:.:.....::|..||           ::||:  |:...|:::|..|||:.|.|.|.  :.:|
Human   169 TQLIDDPFIPGLLSNTGL-----------VRQLV--LDNPHMQQLIQHNPEIGHILNNPEIMRQT 220

  Fly   206 -----DPATFEVFQRNQEELMN---MISGG 227
                 :||..:...|:|:.:::   .|.||
Human   221 LEFLRNPAMMQEMIRSQDRVLSNLESIPGG 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	48/225 (21%)
		UBQ	1..76	CDD:294102	13/52 (25%)
		UBA1_Rad23_like	110..148	CDD:270466	6/41 (15%)
		XPC-binding	172..227	CDD:286376	17/64 (27%)
		UBA2_Rad23_like	245..282	CDD:270467
UBQLN3	NP_001334025.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	102..124		5/21 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	277..330
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..399
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	412..447
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810