DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10694 and UBQLN2

DIOPT Version :9

Sequence 1:NP_651212.1 Gene:CG10694 / 42855 FlyBaseID:FBgn0039147 Length:290 Species:Drosophila melanogaster
Sequence 2:NP_038472.2 Gene:UBQLN2 / 29978 HGNCID:12509 Length:624 Species:Homo sapiens


Alignment Length:277 Identity:64/277 - (23%)
Similarity:118/277 - (42%) Gaps:62/277 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 ESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAEDKIIVLMGKKKVDKSSPE 83
            |:..|:..|:.:..  ......:.|.||::|:|::|...|.::.|.:...:.|:.|   .::.|:
Human    50 ENSSVQQFKEAISK--RFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIK---SQNRPQ 109

  Fly    84 EKVAPTPPLAAGPNVLRTEDVVP-----SLAPNDQ--------WVSDLMSMGYG-------EEEV 128
            .: :..|..|||.|.  |....|     .::.|..        .::.|.|:|..       :.::
Human   110 GQ-STQPSNAAGTNT--TSASTPRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQSQM 171

  Fly   129 RSALRASFNHPERAIEYLINGIPQEVVSEQGLAAIPSVQTSDQLQQLMADLNITRMREMINQNPE 193
            :..|.||   ||..|:.:.|...|.::|...|          ..|.:||:   .:|:::|.:|||
Human   172 QQQLMAS---PEMMIQIMENPFVQSMLSNPDL----------MRQLIMAN---PQMQQLIQRNPE 220

  Fly   194 LIHRLMNR--LAET-----DPATFEVFQRNQE-ELMNM--ISGGAS---RTPNEIEHLQITLTAE 245
            :.|.|.|.  :.:|     :||..:...|||: .|.|:  |.||.:   |...:|:...:....|
Human   221 ISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQE 285

  Fly   246 E-----TAAVGRLEALG 257
            :     .|:||...:.|
Human   286 QFGGNPFASVGSSSSSG 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10694NP_651212.1 rad23 1..284 CDD:273167 64/277 (23%)
UBQ 1..76 CDD:294102 13/56 (23%)
UBA1_Rad23_like 110..148 CDD:270466 10/52 (19%)
XPC-binding 172..227 CDD:286376 20/64 (31%)
UBA2_Rad23_like 245..282 CDD:270467 5/18 (28%)
UBQLN2NP_038472.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..32
UBQ 33..103 CDD:214563 12/54 (22%)
hPLIC_N 33..103 CDD:176403 12/54 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 106..141 9/37 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 287..349 4/16 (25%)
STI1 382..426 CDD:128966
12 X 3 AA tandem repeats of P-X-X 491..526
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 512..556
UBA_PLICs 581..620 CDD:270582
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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