DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and Ubqlnl

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_941026.2	Gene:	Ubqlnl / 244179	MGIID:	2685336	Length:	610	Species:	Mus musculus

Alignment Length:	255	Identity:	60/255 - (23%)
Similarity:	90/255 - (35%)	Gaps:	76/255 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAEDKIIVLMGKKKVDKSSPEEKVA 87
            ||..|:.|....:..|  |.|.|::.||:::|...||:..|.:..||.::.|.|
Mouse    52 VRQFKEILSAHFKCQM--EQLVLVFMGRLLKDHDTLSQRGITDGHIIHVVIKSK----------- 103

  Fly    88 PTPPLAAGPNVLRTEDVVPSLAPNDQWVSD----------LMSMGYGEEEVRSALRASFNHPERA 142
                  .||..|...  ..:|..|:....|          ..|.|..|.:|.|:|......|:..
Mouse   104 ------HGPRSLAHS--FRNLVTNNPCHQDRNPKGNSSMVCQSAGMNETKVESSLLMEPEAPKVG 160

  Fly   143 IEYLINGIPQEVVSEQGLAAIPSVQTSDQL--QQLMADLNITR--------MREMINQNPELIHR 197
            .|      ..||.|.:.:|     |..:.|  |.|:::::...        |.|:|.||||:.|.
Mouse   161 TE------SPEVGSLEHIA-----QVLENLCVQSLLSNMDFVHQMPPEQPYMEELIQQNPEVSHL 214

  Fly   198 LMNR--LAET-----------------DPATFEVFQRNQEELMNMISGGASRTPNEIEHL 238
            |.|.  |.:|                 .||....:..|.:..:     |....||...||
Mouse   215 LDNSEILCQTLELVRHLAIIQEIMQIQQPAQNPEYPPNSQPFL-----GLETVPNGNNHL 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	60/255 (24%)
		UBQ	1..76	CDD:294102	17/52 (33%)
		UBA1_Rad23_like	110..148	CDD:270466	10/47 (21%)
		XPC-binding	172..227	CDD:286376	18/83 (22%)
		UBA2_Rad23_like	245..282	CDD:270467
Ubqlnl	NP_941026.2	UBQ	31..101	CDD:214563	16/50 (32%)
		UBQ	31..101	CDD:294102	16/50 (32%)
		UBA_PLICs	567..606	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810