DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and Ubqln3

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001371113.1	Gene:	Ubqln3 / 244178	MGIID:	3045291	Length:	681	Species:	Mus musculus

Alignment Length:	237	Identity:	52/237 - (21%)
Similarity:	102/237 - (43%)	Gaps:	61/237 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAED---KIIVLMGKKKVDKSSPEE 84
            :|.||:|:.:..: |.| ..|.||::|:|::|...|::..:.:.   .:::.|.::.:...
Mouse    66 IRQLKEKISHRFK-AHP-NQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTIGTE---- 124

  Fly    85 KVAPTPPLA-AGPNVLRTEDVVPSLAPNDQWVSDL------------------MSMGYGEEEVRS 130
              .|:||:: .|||        |...|....|..:                  ::.|...::..|
Mouse   125 --CPSPPVSIPGPN--------PGEIPQSSSVYSVDGSPSFSLGVLTGLSGLGLTSGSFSDQPGS 179

  Fly   131 ALRASFNHPERAIEYLINGIPQEVVSEQGLAAIPSVQTSDQLQQLMADLNITRMREMINQNPELI 195
            .:....:.||...:.:.:...|.::|..||           ::||:  |:...|:.:|.||||:.
Mouse   180 LMWQHISVPELVAQLVDDPFIQGLLSNTGL-----------VRQLV--LDNPHMQHLIQQNPEIG 231

  Fly   196 HRLMNR--LAET-----DPATFEVFQRNQEE-LMNM--ISGG 227
            |.|.|.  :.:|     :|:..:...|:|:. |.|:  |.||
Mouse   232 HILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSNLESIPGG 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	52/237 (22%)
		UBQ	1..76	CDD:294102	14/55 (25%)
		UBA1_Rad23_like	110..148	CDD:270466	6/55 (11%)
		XPC-binding	172..227	CDD:286376	19/64 (30%)
		UBA2_Rad23_like	245..282	CDD:270467
Ubqln3	NP_001371113.1	Ubl_PLICs	43..115	CDD:340506	13/50 (26%)
		STI1	212..256	CDD:128966	14/45 (31%)
		UBA_PLICs	641..678	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810