DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and C16C8.11

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_494548.1	Gene:	C16C8.11 / 173690	WormBaseID:	WBGene00015849	Length:	214	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	38/231 - (16%)
Similarity:	85/231 - (36%)	Gaps:	70/231 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 LAPNDQWVSDLMSMGYGEEEVRSALRASF---------NHPERAIEYLINGIPQEVVSEQG---- 159
            :|.::..:|:...:.....:::|.|...|         |...:|.:.|...:.::...:..
Worm     1 MADSNDLMSEFQKLQQETSKIQSHLTKDFLSSSAKLSENRVLQATQELCGKLTEKQKVQDDTINL 65

  Fly   160 -LAAIPSVQTS-----DQLQQLMADLNITRM------REMINQNPELIHRLMNRLAETDPATFEV 212
             |:|:..:|.:     :|...:.:.|:|.:.      |::|.|.|.:..:.:...::..|
Worm    66 LLSALGQIQENQNKILNQFASMQSQLDIVKRRQDAYERDLIQQKPSVPEQKVGESSKKSP----- 125

  Fly   213 FQRNQEELMNMISGGASRTPNEIEHLQITLTAEETAAVGRLEALG---FERVMAVQAYLACD--- 271
              |:.|..:..:     .|..::..|.|.::..     |||.::|   .|.|..::..:.|.
Worm   126 --RSAESALKYV-----ETCTKVVDLCIAVSMP-----GRLFSIGANKMESVEQLKMKIECQTGI 178

  Fly   272 ---------------KDEQLA-------AEVLIRQS 285
                           .|::||       .|:|:|.|
Worm   179 PRTKFWLRLHGKPLYDDKKLADYKWDTSVELLVRAS 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	36/228 (16%)
		UBQ	1..76	CDD:294102
		UBA1_Rad23_like	110..148	CDD:270466	7/46 (15%)
		XPC-binding	172..227	CDD:286376	9/60 (15%)
		UBA2_Rad23_like	245..282	CDD:270467	11/64 (17%)
C16C8.11	NP_494548.1	COG5391	<9..>111	CDD:227680	16/101 (16%)
C16C8.11	NP_494548.1	UBQ	149..212	CDD:214563	12/67 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900