DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10694 and Ubqln1

DIOPT Version :9

Sequence 1:	NP_651212.1	Gene:	CG10694 / 42855	FlyBaseID:	FBgn0039147	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_446199.2	Gene:	Ubqln1 / 114590	RGDID:	620745	Length:	582	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	62/283 - (21%)
Similarity:	120/283 - (42%)	Gaps:	66/283 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLSIRMLDQRTITLEMNESQEVRALKQKLGNLPEVAMPAENLQLIYSGRIMEDAMPLSEYRIAE 65
            ||::::...::. ...:.|:..|:..|:::..  ......:.|.||::|:|::|...||::.|.:
  Rat    28 MKVTVKTPKEKE-EFAVPENSSVQQFKEEISK--RFKSHIDQLVLIFAGKILKDQDTLSQHGIHD 89

  Fly    66 DKIIVLMGK---KKVDKSSPEEKV---------APTPPLAAGPNVLRTEDVVPSLAPNDQW---- 114
            ...:.|:.|   :..|.|:.:...         ||.....:||            |.|..:
  Rat    90 GLTVHLVIKTQNRPQDNSAQQTNTTGNSVTSSPAPDSNPTSGP------------AANSSFGLGG 142

  Fly   115 ---VSDLMSMGYGE---EEVRSAL-RASFNHPERAIEYLINGIPQEVVSEQGLAAIPSVQTSDQL 172
               ::.|.|:|...   .|::|.: |...::||..::.:.|...|.::|...|          ..
  Rat   143 LGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDL----------MR 197

  Fly   173 QQLMADLNITRMREMINQNPELIHRLMN--------RLAETDPATFEVFQRNQEE-LMNM--ISG 226
            |.:||:   .:|:::|.:|||:.|.|.|        .||. :||..:...|||:. |.|:  |.|
  Rat   198 QLIMAN---PQMQQLIQRNPEISHMLNNPDIMRQTLELAR-NPAMMQEMMRNQDRALSNLESIPG 258

  Fly   227 GAS---RTPNEIEHLQITLTAEE 246
            |.:   |...:|:...:....|:
  Rat   259 GYNALRRMYTDIQEPMLNAAQEQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10694	NP_651212.1	rad23	1..284	CDD:273167	62/283 (22%)
		UBQ	1..76	CDD:294102	16/77 (21%)
		UBA1_Rad23_like	110..148	CDD:270466	9/48 (19%)
		XPC-binding	172..227	CDD:286376	21/65 (32%)
		UBA2_Rad23_like	245..282	CDD:270467	1/2 (50%)
Ubqln1	NP_446199.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		UBQ	28..98	CDD:214563	15/72 (21%)
		hPLIC_N	28..98	CDD:176403	15/72 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	102..136		7/45 (16%)
		Interaction with UBXN4. /evidence=ECO:0000250\|UniProtKB:Q9UMX0	169..422		32/127 (25%)
		STI1	173..210	CDD:128966	10/49 (20%)
		TFIIA	285..>447	CDD:281188
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..365
		STI1	384..416	CDD:128966
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	481..513
		UBA_PLICs	539..578	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810