Protein Alignment Syx1A and STX7

DIOPT Version :10

• Sequence 1: NP_001189276.1
• Gene: Syx1A / 42854
• FlyBaseID: FBgn0013343
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_003560.2
• Gene: STX7 / 8417
• HGNCID: 11442
• Length: 261
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 62/250 - (24%)
• Similarity: 120/250 - (48%)
• Gaps: 17/250 - (6%)

  Fly    46 MIDKVQDNVEEVKKKHSAI------LSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIE 104
            :..::..|::::.:....|      |..||...:.:|:|:..    ::..|::   .|..::.|:
Human    14 LAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQK----QQYTNQL---AKETDKYIK 71

  Fly   105 QEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCK---GRIQRQLEITGRPTNDD 166
            :......:.::.|.||.|...|..:|...:|.:.:.|....||.|   .|::....::|....|.
Human    72 EFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDS 136

  Fly   167 ELEKMLEEGNSSVFTQGIIMETQQAKQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGE 231
            ..|:.|....|....|..:.:.:..:..|..|..|...|.:||..|.:::::|.|:.|::..||:
Human   137 SKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGD 201

  Fly   232 MIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKIMILICLTVLGILAASYV 286
            :||.||.:||:|..:||.|.|...:|..||.|: ||.:.|:|.:.|:|:...|.:
Human   202 VIDSIEANVENAEVHVQQANQQLSRAADYQRKS-RKTLCIIILILVIGVAIISLI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	35..230	CDD:459942	38/192 (20%)
		SNARE	231..281	CDD:461727	21/49 (43%)
STX7	NP_003560.2	Syntaxin_2	18..119	CDD:464199	21/107 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..148		4/18 (22%)
		SNARE_syntaxin7	168..227	CDD:277228	22/58 (38%)