DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx1A and SYP111

DIOPT Version :9

Sequence 1:	NP_001189276.1	Gene:	Syx1A / 42854	FlyBaseID:	FBgn0013343	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_172332.1	Gene:	SYP111 / 837378	AraportID:	AT1G08560	Length:	310	Species:	Arabidopsis thaliana

Alignment Length:	318	Identity:	82/318 - (25%)
Similarity:	153/318 - (48%)	Gaps:	42/318 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTKD-------RLAALHAAQSDDEEETEVA-VNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEV 57
            |||.       :.||:...::..:.:.|:| ...|..|..:..|..:.|.::..:..:.:.:..:
plant     5 MTKSFMSYVDLKKAAMKDMEAGPDFDLEMASTKADKMDENLSSFLEEAEYVKAEMGLISETLARI 69

  Fly    58 KKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRG---KLKGIEQNIEQEEQQNKSSADL--- 116
            ::.|.        :.|...:.|.:.:...|.:|.:..   |.|.|:..:|:.::.||....|
plant    70 EQYHE--------ESKGVHKAESVKSLRNKISNEIVSGLRKAKSIKSKLEEMDKANKEIKRLSGT 126

  Fly   117 ---RIRKTQHSTLSRKFVEVMTEY----NRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEE 174
               |.|....:.|.:|..|||.|:    .:..::|:|..:   :|...:||...||:.:||::.:
plant   127 PVYRSRTAVTNGLRKKLKEVMMEFQGLRQKMMSEYKETVE---RRYFTVTGEHANDEMIEKIITD 188

  Fly   175 --GNSSVFTQGIIMETQQAK--QTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDR 235
              |.....|:. |.|..:.|  :|:.:|:.|:....::|.|:.|||.:|:|||::||||||.:|.
plant   189 NAGGEEFLTRA-IQEHGKGKVLETVVEIQDRYDAAKEIEKSLLELHQVFLDMAVMVESQGEQMDE 252

  Fly   236 IEYHVEHAMDYVQTATQDTKKALKYQSKARRKK-----IMILICLTVLGILAASYVSS 288
            ||:||.:|..||.....:.|.|..:|..:|:..     :::||.|.|:..:..|:.||
plant   253 IEHHVINASHYVADGANELKTAKSHQRNSRKWMCIGIIVLLLIILIVVIPIITSFSSS 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	33..230	CDD:395647	51/213 (24%)
Syx1A	NP_001189276.1	SNARE	231..281	CDD:399038	17/54 (31%)
SYP111	NP_172332.1	Syntaxin	45..247	CDD:279182	51/213 (24%)
		SynN	45..199	CDD:238105	33/164 (20%)
		SNARE_syntaxin1-like	211..273	CDD:277201	26/61 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2612
eggNOG	1	0.900	-	-		E1_COG5074
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2016
OMA	1	1.010	-	-		QHG53912
OrthoDB	1	1.010	-	-		D1033833at2759
OrthoFinder	1	1.000	-	-		FOG0000185
OrthoInspector	1	1.000	-	-		otm2646
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19957
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980