Protein Alignment Syx1A and Stx12

DIOPT Version :10

• Sequence 1: NP_001189276.1
• Gene: Syx1A / 42854
• FlyBaseID: FBgn0013343
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: XP_006239128.1
• Gene: Stx12 / 65033
• RGDID: 620977
• Length: 321
• Species: Rattus norvegicus
• Alignment Length: 247
• Identity: 59/247 - (23%)
• Similarity: 105/247 - (42%)
• Gaps: 31/247 - (12%)

  Fly    35 DFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLM---ADIKKNANRVRGKL 96
            ||.:.::...|.|.::.....::|...|. |...|...|.::.|:...   ..:.|..|.:..:|
  Rat    21 DFNSIIQTCSGNIQRISQATAQIKNLMSQ-LGTKQDSSKLQENLQQFQHSTNQLAKETNELLKEL 84

  Fly    97 KGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGR 161
            ..:...:...||        |.:|.|...|...|...:..:...|....|:.|..|.|....:..
  Rat    85 GSLPLPLSASEQ--------RQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRL 141

  Fly   162 PTNDDELEKML------EEGNSSVFTQGIIMETQQ-----AKQTLADIEARHQDIMKLETSIKEL 215
            ...|.:.|:.|      ||.|.        |::|:     .:|.|..|:.|...|.:||..|.::
  Rat   142 SAEDRQREEQLVSFDSHEEWNQ--------MQSQEEEAAITEQDLELIKERETAIQQLEADILDV 198

  Fly   216 HDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRK 267
            :.:|.|:||::..||::||.||.:||.:..:|:.|:...::|..||...|::
  Rat   199 NQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQDLRRQE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	35..230	CDD:459942	45/208 (22%)
		SNARE	231..281	CDD:461727	12/37 (32%)
Stx12	XP_006239128.1	Syntaxin_2	30..132	CDD:464199	21/110 (19%)
		SNARE_syntaxin12	181..244	CDD:277229	21/62 (34%)