Protein Alignment Syx1A and Stx1b

DIOPT Version :10

• Sequence 1: NP_001189276.1
• Gene: Syx1A / 42854
• FlyBaseID: FBgn0013343
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: XP_006508107.1
• Gene: Stx1b / 56216
• MGIID: 1930705
• Length: 406
• Species: Mus musculus
• Alignment Length: 276
• Identity: 196/276 - (71%)
• Similarity: 231/276 - (83%)
• Gaps: 4/276 - (1%)

  Fly    11 AAQSDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTK 75
            |..||||||   .|:|| .|.:||:||.|||||||.|:|:.::||:|||:|||||:||..|||||
Mouse   129 AKDSDDEEE---VVHVD-RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTK 189

  Fly    76 QELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRT 140
            ||||||.|||||.||:||.|||.|||:|||||..|:|||||||||||||||||||||||||||.|
Mouse   190 QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNAT 254

  Fly   141 QTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGNSSVFTQGIIMETQQAKQTLADIEARHQDI 205
            |:.||:|||.|||||||||||.|.::|||.|||.|..::||..|.|::|..||.|.:||.||.:|
Mouse   255 QSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEI 319

  Fly   206 MKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKIM 270
            :||||||:||||||:||||||||||||||||||:|||::|||:.|..|||||:||||||||||||
Mouse   320 IKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIM 384

  Fly   271 ILICLTVLGILAASYV 286
            |:||..|||::.||.:
Mouse   385 IIICCVVLGVVLASSI 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	35..230	CDD:459942	141/194 (73%)
		SNARE	231..281	CDD:461727	38/49 (78%)
Stx1b	XP_006508107.1	SynN	147..298	CDD:238105	112/150 (75%)
		SNARE_syntaxin1	308..376	CDD:277233	50/67 (75%)