DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx1A and psy1

DIOPT Version :9

Sequence 1:	NP_001189276.1	Gene:	Syx1A / 42854	FlyBaseID:	FBgn0013343	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_588053.1	Gene:	psy1 / 2539377	PomBaseID:	SPCC825.03c	Length:	284	Species:	Schizosaccharomyces pombe

Alignment Length:	259	Identity:	75/259 - (28%)
Similarity:	134/259 - (51%)	Gaps:	14/259 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 MDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDE----KTKQELEDLMADIKKNANRVR 93
            |.:||.:::.||..|.:::|||..::..|..  |..:.||    .|.:.||...:|.::....|:
pombe    18 MGEFFEEIDHIRDAIRQIEDNVGRIEMLHQQ--SLQEIDEANIAATTRHLEGYTSDTRRLQTSVQ 80

  Fly    94 GKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEI 158
            ..::    ::|.:..|.....|...||||...:.:||::.:..:.:.:..||.:.:.|::|||||
pombe    81 LAIR----SLESQNMQLPPDNDTATRKTQTEAVKKKFMDQIRHFLQIEKTYRAQYEQRMRRQLEI 141

  Fly   159 TG-RPTNDDELEKMLEEGNSSVFTQGIIMETQ--QAKQTLADIEARHQDIMKLETSIKELHDMFM 220
            .. |.|.||....:.||....||.|.::...:  :|:..|.:::.||.||.::|.:|.||..:|.
pombe   142 ANPRATEDDFQTAINEENGGQVFAQALLRSNRSGEARTALREVQERHADIKRIERTIAELAQLFQ 206

  Fly   221 DMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKK-IMILICLTVLGILAA 283
            |||.:|:.|..|:|:|.....:....:...||...:|:|....||:|| |...||:.::.::.|
pombe   207 DMATMVQEQEPMVDKIVTDAVNVRTNMGEGTQHMDRAIKSARAARKKKWICFGICVVIICVIVA 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	33..230	CDD:395647	59/203 (29%)
Syx1A	NP_001189276.1	SNARE	231..281	CDD:399038	14/50 (28%)
psy1	NP_588053.1	COG5074	1..284	CDD:227406	75/259 (29%)
		SynN	18..167	CDD:238105	43/154 (28%)
		SNARE_Sso1	181..244	CDD:277202	20/62 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I1890
eggNOG	1	0.900	-	-		E1_COG5074
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37941
Inparanoid	1	1.050	118	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG53912
OrthoFinder	1	1.000	-	-		FOG0000185
OrthoInspector	1	1.000	-	-		oto100518
orthoMCL	1	0.900	-	-		OOG6_100497
Panther	1	1.100	-	-	O	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1024
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.900