Protein Alignment Syx1A and Stx1a

DIOPT Version :10

• Sequence 1: NP_001189276.1
• Gene: Syx1A / 42854
• FlyBaseID: FBgn0013343
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_058081.2
• Gene: Stx1a / 20907
• MGIID: 109355
• Length: 288
• Species: Mus musculus
• Alignment Length: 288
• Identity: 202/288 - (70%)
• Similarity: 241/288 - (83%)
• Gaps: 2/288 - (0%)

  Fly     3 KDRLAALHAAQSDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSA 67
            |||...|..|:..|::: :|.|.|| .|.:||:||.|||||||.|||:.:||||||:||||||::
Mouse     2 KDRTQELRTAKDSDDDD-DVTVTVD-RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILAS 64

  Fly    68 PQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVE 132
            |..|||||:|||:||:||||.||:||.|||.|||:|||||..|:|||||||||||||||||||||
Mouse    65 PNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVE 129

  Fly   133 VMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGNSSVFTQGIIMETQQAKQTLAD 197
            ||:|||.||:|||||||||||||||||||.|..:|||.|||.||.::|..||||::..:||.|::
Mouse   130 VMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSE 194

  Fly   198 IEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQS 262
            ||.||.:|:||||||:|||||||||||||||||||||||||:||||:|||:.|..|||||:||||
Mouse   195 IETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQS 259

  Fly   263 KARRKKIMILICLTVLGILAASYVSSYF 290
            |||||||||:||..:|||:.||.:...|
Mouse   260 KARRKKIMIIICCVILGIIIASTIGGIF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	35..230	CDD:459942	145/194 (75%)
		SNARE	231..281	CDD:461727	38/49 (78%)
Stx1a	NP_058081.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		6/18 (33%)
		SynN	30..181	CDD:238105	114/150 (76%)
		SNARE_syntaxin1	191..259	CDD:277233	52/67 (78%)