Protein Alignment Syx1A and STX1B

DIOPT Version :10

• Sequence 1: NP_001189276.1
• Gene: Syx1A / 42854
• FlyBaseID: FBgn0013343
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_443106.1
• Gene: STX1B / 112755
• HGNCID: 18539
• Length: 288
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 200/285 - (70%)
• Similarity: 237/285 - (83%)
• Gaps: 5/285 - (1%)

  Fly     3 KDRLAALHAAQ-SDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILS 66
            |||...|.:|: ||||||   .|:|| .|.:||:||.|||||||.|:|:.::||:|||:|||||:
Human     2 KDRTQELRSAKDSDDEEE---VVHVD-RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILA 62

  Fly    67 APQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFV 131
            ||..|||||||||||.|||||.||:||.|||.|||:|||||..|:||||||||||||||||||||
Human    63 APNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFV 127

  Fly   132 EVMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGNSSVFTQGIIMETQQAKQTLA 196
            |||||||.||:.||:|||.|||||||||||.|.::|||.|||.|..::||..|.|::|..||.|.
Human   128 EVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALN 192

  Fly   197 DIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQ 261
            :||.||.:|:||||||:||||||:||||||||||||||||||:|||::|||:.|..|||||:|||
Human   193 EIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQ 257

  Fly   262 SKARRKKIMILICLTVLGILAASYV 286
            ||||||||||:||..|||::.||.:
Human   258 SKARRKKIMIIICCVVLGVVLASSI 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx1A	NP_001189276.1	Syntaxin	35..230	CDD:459942	141/194 (73%)
		SNARE	231..281	CDD:461727	38/49 (78%)
STX1B	NP_443106.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		11/20 (55%)
		SynN	29..180	CDD:238105	112/150 (75%)
		SNARE_syntaxin1	190..258	CDD:277233	50/67 (75%)