Protein Alignment SMC1 and TTN8

DIOPT Version :10

• Sequence 1: NP_651211.2
• Gene: SMC1 / 42853
• FlyBaseID: FBgn0040283
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_001319748.1
• Gene: TTN8 / 824632
• AraportID: AT3G54670
• Length: 1218
• Species: Arabidopsis thaliana
• Alignment Length: 1246
• Identity: 424/1246 - (34%)
• Similarity: 718/1246 - (57%)
• Gaps: 78/1246 - (6%)

  Fly    30 IEMENFKSYRGHIVVGPLKQFNAVIGPNGSGKSNFMDAISFVMGEKTSSLRVKRLNDLIHG--SS 92
            :||||||||:||.:|||.|.|.|:||||||||||.|||||||:|.:|..||..:|.|||:.  ..
plant    14 LEMENFKSYKGHQLVGPFKDFTAIIGPNGSGKSNLMDAISFVLGVRTGQLRGSQLKDLIYAFDDR 78

  Fly    93 IGKPVSRSCYVTAKFVLNEERHMDFQRAVI-GGSSEYRINGESVSSSTYLNKLEKIGINVKAKNF 156
            ..:...|..:|...:.:::...:.|.|::. .|.|||||:...|:...|..||..:||.|||:||
plant    79 DKEQRGRKAFVRLVYQMDDGVELRFTRSITSAGGSEYRIDNRVVNLDEYNGKLRSLGILVKARNF 143

  Fly   157 LVFQGAVENIAMKTPKERTALFEEISGSGLLKDDYNRLKQEMIVAEEETQFTYQKKKGIAAERKE 221
            |||||.||:||.|.|||.|.|.||||||..||.:|..|:::...|||:....|||||.|..|:|.
plant   144 LVFQGDVESIASKNPKELTGLLEEISGSEELKKEYEGLEEKKASAEEKAALIYQKKKTIGNEKKL 208

  Fly   222 AKHEKMEADRYTRLQNEYNEKQVEYQLFRLFHVERDIRKFTSDLEVRQQEVKAVEQRKEAADEIL 286
            .|.:|.||:::.|||.|....:.|..|::|:::|.||.|...|::..:...|.|.:..|..:...
plant   209 KKAQKEEAEKHLRLQEELKALKRERFLWQLYNIENDIEKANEDVDSEKSNRKDVMRELEKFEREA 273

  Fly   287 REKKKDAGKITRDLAKIDQEIREFETQMNKRRPLYIKAKEKVTHCKKKLISLQKTLETAREADNA 351
            .::|.:..|..:::|:.:::|.|..:::.|.:|..::.||::...|.|:.:.:|.::..::....
plant   274 GKRKVEQAKYLKEIAQREKKIAEKSSKLGKIQPELLRFKEEIARIKAKIETNRKDVDKRKKEKGK 338

  Fly   352 HQSDIRKLEKQLADVEALKKRFEDEIENESQRRGKSVNMEEGLVQEYDRLKQEAEATATQYRSEL 416
            |..:|.:::|.:.::....:.|..:.::.|   || :.|.:..:|:|.|||:||.....:.|.|.
plant   339 HSKEIEQMQKSIKELNKKMELFNKKRQDSS---GK-LPMLDSQLQDYFRLKEEAGMKTIKLRDEH 399

  Fly   417 DSVNREQKSEQDTLDGETNRRASVEESFKKLTLQR---EEAVKR-RDKLMDHIKSSQAALEEQNR 477
            :.:.|:::::.:.|       .::||::::|..::   :|.:|| :|:..:...||.....|...
plant   400 EVLERQRRTDLEAL-------RNLEENYQQLINRKNDLDEQIKRFKDRQGEIETSSSKYKNETTS 457

  Fly   478 IKDELR----RDVGTSKEKIAEKQRELEDVRDQLGDAKSDKHEDARRKKKQEVVELFKKQVPGVY 538
            :|.|||    :.| .::|..|:.:..:.::.|||.|..::::|:.|..:..:.||..|:...||:
plant   458 LKTELRALQEKHV-NAREASAKLKTRIAELEDQLSDLTAERYENERDSRLTQAVESLKRLFQGVH 521

  Fly   539 DRMINMCQPTHKRYNVAVTKVLGKFMEAIIVDTEKTARHCIQILKEQMLEVETFLPLDYLQVKPL 603
            .||.::|:|..|:||:|||..:|:||:|::|:.|.|.:.||:.||||.|...||:||..::||.:
plant   522 GRMTDLCRPNRKKYNLAVTVAMGRFMDAVVVEDENTGKDCIKYLKEQRLPPMTFIPLQSVRVKQV 586

  Fly   604 KERLRNISDPRNVRLVFDVLKFEPQEIERAVLFATGNALVCETPEDAMKVAYEIDRSRFDALALD 668
            .|||||:..  ..:|||||::|:| |:|:|||:|.||.|||:..|:|..:::  ...||..:.:|
plant   587 FERLRNLGG--TAKLVFDVIQFDP-ELEKAVLYAVGNTLVCDELEEAKVLSW--SGERFKVVTVD 646

  Fly   669 GTFYQKSGLISGG-SHDLARKAKRWDEKHMAQLKMQKERLQEELKELVKKSRKQSELATVESQIK 732
            |....|:|.::|| |..:..|:.:||:|.:..||..||..:::|:.:......|.:.:.:..:|.
plant   647 GILLTKAGTMTGGTSGGMEAKSNKWDDKKIEGLKKNKEDFEQQLENIGSIREMQMKESEISGKIS 711

  Fly   733 GLENRLKYSMVDLESSKKSISQYDNQLQQVQSQLDEFGPKILEIERRMQNREEHIQEIKENMNNV 797
            |||.:::|:.::.:|.|..:.|.:.:.:.:..::|...|::.:....:..|:..:.::::.||.:
plant   712 GLEKKIQYAEIEKKSIKDKLPQLEQEERNIIEEIDRIKPELSKARTEVDKRKTEMNKLEKRMNEI 776

  Fly   798 EDKVYASFCRRLGVKNIRQYEERELVMQQERARKRAEFEQQIDSINSQLDFEKQKDTKKNVERWE 862
            .|::|..|.:.:||.|||.|||.:|...::.|.:|.|...|:..:..||::|:.:|....:.:.|
plant   777 VDRIYKDFSQSVGVPNIRVYEETQLKTAEKEAEERLELSNQLAKLKYQLEYEQNRDVGSRIRKIE 841

  Fly   863 RSVQDEEDALEGL-------KLAEARYLKEIDEDKEKMEKFKQDKQAKKQAVDDMEEDISKARKD 920
            .|:...|..|||:       |....:...||:..|::||:.||..:..::.:.|.::..|:|...
plant   842 SSISSLETDLEGIQKTMSERKETAVKITNEINNWKKEMEECKQKSEEYEKEILDWKKQASQATTS 906

  Fly   921 VANLAKEIHNVGSHLSAVESKIEAKKNERQNILLQAKTDCIVVPLLRGSLDDAVRQSDPDVPSTS 985
            :..|.::||       :.|::||...:::|.|..:.:.:.|.:|:    |.||:.:.|.|.|
plant   907 ITKLNRQIH-------SKETQIEQLISQKQEITEKCELEHITLPV----LSDAMEEDDSDGP--- 957

  Fly   986 AAMENIIEVDYSSLPREYTKLKDDSAFKKTHEMLQKDLQSKLDVLERIQTPNMKALQKLDAVTEK 1050
                   :.|:|.|.|.|.:.:..||.:|.....::.::||...:|| ..||::||.:.:|:.||
plant   958 -------QFDFSELGRAYLQERRPSAREKVEAEFRQKIESKTSEIER-TAPNLRALDQYEAIQEK 1014

  Fly  1051 VQSTNEEFENARKKAKRAKAAFERVKNERSSRFVACCQHISDAIDGIYKKLARNE----AAQAYI 1111
            .:..::|||.|||:.|:...||..||.:|...|:....||:..||.|||:|.::.    ...||:
plant  1015 EKQVSQEFEAARKEEKQVADAFNTVKQKRYELFMEAFNHIASNIDKIYKQLTKSNTHPLGGTAYL 1079

  Fly  1112 GPDNPEEPYLDGINYNCVAPGKRFQPMNNLSGGEKTIAALALLFSTHSFHPAPFFVLDEIDAALD 1176
            ..:|.::|:|.||.|..:.|.|||:.|..|||||||:||||||||.||:.|:|||:|||:|||||
plant  1080 NLENEDDPFLHGIKYTTMPPTKRFRDMEQLSGGEKTVAALALLFSIHSYRPSPFFILDEVDAALD 1144

  Fly  1177 NTNIGKVASYIRDHT-------------TNLQTIVISLKEEFYGHADALVGI-TPGEGDCLVSNV 1227
            |.|:.|||.:||..:             ...|:||||||:.||..|:||||: ...|..|  |:.
plant  1145 NLNVAKVAKFIRSKSCQAARDNQDAEDGNGFQSIVISLKDSFYDKAEALVGVYRDTERSC--SST 1207

  Fly  1228 YIMDLTTFEDT 1238
            ...||..::::
plant  1208 MSFDLRNYQES 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC1	NP_651211.2	SMC_N	26..1222	CDD:481474	420/1228 (34%)
TTN8	NP_001319748.1	SMC_N	11..1196	CDD:481474	418/1220 (34%)