Protein Alignment SMC1 and TTN7

DIOPT Version :10

• Sequence 1: NP_651211.2
• Gene: SMC1 / 42853
• FlyBaseID: FBgn0040283
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_180285.4
• Gene: TTN7 / 817259
• AraportID: AT2G27170
• Length: 1204
• Species: Arabidopsis thaliana
• Alignment Length: 1311
• Identity: 296/1311 - (22%)
• Similarity: 553/1311 - (42%)
• Gaps: 267/1311 - (20%)

  Fly    26 FLEYIEMENFKSYRGHIVVGPL-KQFNAVIGPNGSGKSNFMDAISFVMGEKTSSLRVKRLNDLIH 89
            |::.:.:|.||||:..:..... .:.|.|:|.||||||||..||.||:.:...:||.:..:.|:|
plant     2 FIKQVIIEGFKSYKEQVATEEFSNKVNCVVGANGSGKSNFFHAIRFVLSDIYQNLRSEDRHALLH 66

  Fly    90 GSSIGKPVSRSCYVTAKFVLNEER------HMDFQRAVIGGSSEYRINGESVSSSTYLNKLEKIG 148
            ..:..:.|  |.:|...|..::.|      .:..:|.|.....:|.::|:.::....:|.||..|
plant    67 EGAGHQVV--SAFVEIVFDNSDNRFPVDKEEIRLRRTVGLKKDDYFLDGKHITKGEVMNLLESAG 129

  Fly   149 INVKAKNFLVFQGAVENIAMKTPKERTALFEEISGSGLLKDDYNRLKQEMIVAEEETQFTYQKKK 213
            .:.....::|.||.:.::.:....||..|.:||.|:.:.::   |.::.:.:.:|    |..|:|
plant   130 FSRANPYYVVQQGKIASLTLMKDIERLDLLKEIGGTRVYEE---RRRESLRIMQE----TGNKRK 187

  Fly   214 GIAA------ER-KEAKHEKMEADRYTRLQNEYNEKQVEYQLF-RLFHVERDIRKFTSDLEVRQQ 270
            .|..      || :|...||.|..:|.:|..:  .|.:||.:: :..|   |.|:....:||.:
plant   188 QIIEVVHYLDERLRELDEEKEELRKYQQLDKQ--RKSLEYTIYDKELH---DAREKLEQVEVAR- 246

  Fly   271 EVKAVEQRKEAADEILREKKKDAGK--------ITRDLAKIDQEIREFETQ----MNKRRPLYIK 323
             .||.|:..:..|.:  ||.:|..|        :|::|..:.:|....|.|    :.|:..|.:.
plant   247 -TKASEESTKMYDRV--EKAQDDSKSLDESLKELTKELQTLYKEKETVEAQQTKALKKKTKLELD 308

  Fly   324 AKEKVTHCKKKLISLQKTLETAREADNAHQSDIRKLEKQLADVEALKKRFEDEIENESQRRGKSV 388
            .|:........:.|....||.....:       |:::..|.::||:|..:|.:::.|:|...:..
plant   309 VKDFQDRITGNIQSKNDALEQLNTVE-------REMQDSLRELEAIKPLYESQVDKENQTSKRIN 366

  Fly   389 NMEEGLVQEYDRLKQEAEATATQY----------RSELDSVNREQKSEQDTLDGETNRRASVEES 443
            .:|:.|...|.:     :..|||:          |.|::.:.|       .||..|.:...:::.
plant   367 ELEKTLSILYQK-----QGRATQFSNKAARDKWLRKEIEDLKR-------VLDSNTVQEQKLQDE 419

  Fly   444 FKKLT---LQREEAVKRRD----KLMDHIKSSQAALEEQNRIKDELRRDVGTSKEKIAEKQR--- 498
            ..:|.   .:|:|.:|:.:    :|...|..|......:.|.:||.:|   ..|||..|:.:
plant   420 ILRLNTDLTERDEHIKKHEVEIGELESRISKSHELFNTKKRERDEEQR---KRKEKWGEESQLSS 481

  Fly   499 ELEDVRDQLGDAKSDKHE----DARRKKKQEVVELFKKQVPGVYDRMINM--CQPTHKRYNVAVT 557
            |::.::.:|..||.:...    |.||............::.||:..::.:  |.   :::..||.
plant   482 EIDKLKTELERAKKNLDHATPGDVRRGLNSIRRICADYRINGVFGPLVELVDCD---EKFFTAVE 543

  Fly   558 KVLGKFMEAIIVDTE----KTARHCIQILKEQMLEVETFLPLDYLQVKPLKERLRNISD--PRNV 616
            ...|..:..::|:.:    |..|| :..||...:   |||||:  ::|..:......||  |...
plant   544 VTAGNSLFNVVVENDDISTKIIRH-LNSLKGGRV---TFLPLN--RIKAPRVNYPKDSDAIPLLK 602

  Fly   617 RLVFDVLKFEPQEIERAVLFATGNALVCETPEDAMKVAYEIDRSRFDALALDGTFYQKSGLISGG 681
            :|.|| .||||     |:....|..:||.....|.:||...|   .|.:.::|....:.|.::||
plant   603 KLKFD-SKFEP-----ALGQVFGRTVVCRDLNVATRVAKNDD---LDCITMEGDQVSRKGGMTGG 658

  Fly   682 SHDLARKAKRW-------------DEKHMAQLKMQKERLQEELKELV-KKSRKQSELATVESQIK 732
            .:|..|...|:             .||.:..::.|.:.:.:::.:|| ::.|.:::....:.|::
plant   659 FYDHRRSKLRFMNIIMQNTKSINEKEKELEDVRRQLQVIDQQITQLVTEQQRLEADWTLCKLQVE 723

  Fly   733 GLE------NRLKYSM-VDLESSKKSISQYDNQLQQVQSQLD----EFGPKILEIERRMQNREEH 786
            .|:      |:.|::: ..:|..:|.:.....::.||:|.:.    |.|.::  ::.......|.
plant   724 QLKQEIANANKQKHAIHKAIEYKEKLLGDIRTRIDQVRSSMSMKEAEMGTEL--VDHLTPEEREQ 786

  Fly   787 IQEIKENMNNVEDKVYASFCRRLGVKNIRQYEERELVMQQERARKRAEFEQQIDSINSQLDFEKQ 851
            :.::...:.::::|.:|....|:                 ||..::||.|..|.:
plant   787 LSKLNPEIKDLKEKKFAYQADRI-----------------ERETRKAELEANIAT---------- 824

  Fly   852 KDTKKNVERWERSVQDEEDALEGLKLAEARYLKEIDEDKEKMEKFKQDKQAKKQAVDDMEEDISK 916
             :.|:.:...:.::                  ..||:|     ........|:|.:||.:..:::
plant   825 -NLKRRITELQATI------------------ASIDDD-----SLPSSAGTKEQELDDAKLSVNE 865

  Fly   917 ARKDVANLAKEIHNVGSHLSAVESKIEAKKNERQNILLQAKTDCIVVPLLRGSLDDAVRQSDPDV 981
            |       |||:.:|...:.....:|:..|:|:.. |...:.||      :|:|.|..::
plant   866 A-------AKELKSVCDSIDEKTKQIKKIKDEKAK-LKTLEDDC------KGTLQDLDKK----- 911

  Fly   982 PSTSAAMENIIEVDYSSLPR--EYTK-------LKDDSAF----KKTHEMLQKDLQSKLDVLERI 1033
                  :|.:..:..:.|.:  ||||       |..| ||    :|..:.|||.|....:.|::.
plant   912 ------LEELFSLRNTLLAKQDEYTKKIRGLGPLSSD-AFDTYKRKNIKELQKMLHRCSEQLQQF 969

  Fly  1034 QTPNMKALQKLDAVT---EKVQSTNEEFENARKKAKRAKAAFERVKNERSSR-FVACCQHISDAI 1094
            ...|.|||.:....|   |::|:...|.:...:|.|......::.|:|...| |.....|..|..
plant   970 SHVNKKALDQYVNFTEQREELQNRQAELDAGDEKIKELITVLDQRKDESIERTFKGVAHHFRDVF 1034

  Fly  1095 -----DG-----IYKKLARNEAAQAYIGPDNPEEPYLDG---------INYNCVAPGKRFQPMNN 1140
                 ||     |.||...:...:.....|...|...:|         :..:....|:. |.|..
plant  1035 SELVQDGYGNLIIMKKKDLDNDDEDDDDDDGGREAVTEGRVEKYIGVKVKVSFTGQGET-QLMKQ 1098

  Fly  1141 LSGGEKTIAALALLFSTHSFHPAPFFVLDEIDAALD---NTNIGKVASYIRDH------TTNLQT 1196
            ||||:||:.||||:|:.....||||::.||||||||   .|.:|.:...:.|.      ||..:.
plant  1099 LSGGQKTVVALALIFAIQRCDPAPFYLFDEIDAALDPQYRTAVGNLIRRLADDYGTQFITTTFRP 1163

  Fly  1197 IVISLKEEFYG 1207
            .::.:.::.||
plant  1164 ELVRVADKIYG 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC1	NP_651211.2	SMC_N	26..1222	CDD:481474	296/1311 (23%)
TTN7	NP_180285.4	SMC_N	2..1175	CDD:481474	296/1311 (23%)