| Sequence 1: | NP_651211.2 | Gene: | SMC1 / 42853 | FlyBaseID: | FBgn0040283 | Length: | 1238 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055925.2 | Gene: | SMC5 / 23137 | HGNCID: | 20465 | Length: | 1101 | Species: | Homo sapiens |
| Alignment Length: | 1269 | Identity: | 243/1269 - (19%) |
|---|---|---|---|
| Similarity: | 471/1269 - (37%) | Gaps: | 406/1269 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 30 IEMENFKSYRGHIVVGPLKQFNAVIGPNGSGKSNFMDAISFVMGEKTSSLRVKRLNDLIHGSSIG 94
Fly 95 KPVSRSC----------YVTAKFVLNEERHMDFQRAVIGGSSEYRINGESVSSSTYLNKLEKIGI 149
Fly 150 NVKAKNFLVFQGAVENIAMKTPKERTALFEEISGSGL-------------------LKDDYNRLK 195
Fly 196 QEMIVAEEETQFT-----------------YQKKKGI-AAERKEAKHEKMEADRYTRLQNEYNEK 242
Fly 243 QVEYQLFRLFHVERDIRKF-------TSDLEVRQQEVKAVEQR-KEAADEILREKKKDAGKITRD 299
Fly 300 -LAKIDQEIREFETQMNKRRPLYIKAKEKVTHCKKKLISLQKTLETAREADN------AHQSDIR 357
Fly 358 KL--EKQLADVEALKKRFEDE-IENESQRRGKSVNMEEGLVQEYDRLKQEAEATATQYRSELDSV 419
Fly 420 ----NREQKSEQD-------TLDGETNRRASVEESFKKLTLQREEAVKRRDKLMDHIKSSQAALE 473
Fly 474 EQNRIKDELRRDVGTSKEKIAEKQRELEDVRD----QLGDAKSDKHEDARRKKKQEVVEL----F 530
Fly 531 KKQVPGVYDR----MINMCQPTHKRYNVAVTKVLGKFMEAIIVDTEKTARHCIQILKEQMLEVET 591
Fly 592 FLPLDYLQVKPLKERLRNISDPRNVRLVFDVLKFEPQEIERAVLFATGNALVCETPEDAMKVAYE 656
Fly 657 IDRSRFDALALDGTFYQKSGLISGGSHDLARKAKRWDEKHMAQLKMQKERLQEELKELVKKSRKQ 721
Fly 722 SELATVESQIKGLENRLKYSMVDLESSKKSISQYDNQLQQVQSQLDEFGPKILEIERRMQNREEH 786
Fly 787 IQEIKENMNNVEDKVYASFCRRLGVKNIRQYEERELVMQQERARKRAEFEQQIDSINSQLDFEKQ 851
Fly 852 KDTKKNVERWERSVQDEEDALEG--------LKLAEARYLKEIDEDKEK-MEKFKQDKQAKKQAV 907
Fly 908 DDMEEDISKARKDVANLAKEIHNVGSHLSAVESKIEAKKNERQNILLQAKTDCIVVPLLRGSLDD 972
Fly 973 AVRQSDPDVPSTSAAMENIIEVDYS----------SLPREYTKLKDDSAFKKTHEMLQKDLQSKL 1027
Fly 1028 DVLERIQTPNMKALQKLDAVTEKVQSTNEEFENARKKAKRAKAAFERVKNERSSRFVACCQHISD 1092
Fly 1093 AIDGIYKKLARNEAAQAYIGPDNPEEPYLDGINYNCVAPGKRFQPMNNL--------SGGEKTIA 1149
Fly 1150 ALALLFSTHSFHPAPFFVLDEIDAALDNTNIGKV 1183 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SMC1 | NP_651211.2 | Smc | 26..1216 | CDD:224117 | 243/1269 (19%) |
| ABC_SMC1_euk | 27..>171 | CDD:213242 | 34/150 (23%) | ||
| SMC_hinge | 535..653 | CDD:214944 | 17/121 (14%) | ||
| DUF4700 | <697..>810 | CDD:292399 | 23/112 (21%) | ||
| ABC_SMC1_euk | <1130..1232 | CDD:213242 | 16/62 (26%) | ||
| SMC5 | NP_055925.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..43 | ||
| ABC_SMC5_euk | 51..>196 | CDD:213244 | 37/166 (22%) | ||
| Smc | 53..1055 | CDD:224117 | 243/1269 (19%) | ||
| Flexible hinge | 446..646 | 49/290 (17%) | |||
| ABC_SMC5_euk | <975..1077 | CDD:213244 | 16/64 (25%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1196 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||