DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SMC1 and C44C10.5

DIOPT Version :9

Sequence 1:	NP_651211.2	Gene:	SMC1 / 42853	FlyBaseID:	FBgn0040283	Length:	1238	Species:	Drosophila melanogaster
Sequence 2:	NP_001359562.1	Gene:	C44C10.5 / 183454	WormBaseID:	WBGene00008086	Length:	277	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	60/297 - (20%)
Similarity:	128/297 - (43%)	Gaps:	52/297 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   852 KDTKKNVE---RWERSVQDEEDALEGLKL-------AEARYL-KEIDEDKEKMEKFKQDKQAKKQ 905
            :::|:.||   :.:..:|.|:.....|.|       .|.:.| |::.:::.|:...|..||::|.
Worm     3 EESKQKVEKHTKMKELIQVEQGQFISLHLYRLFLNDLERKSLEKKLTKEQVKLTNIKASKQSQKV 67

  Fly   906 AVDDMEEDISK------------ARKDVANLAKEIHNVGSHLSAVESKIEAKKNERQNILLQAKT 958
            ...|..:.|:|            :|.|..:|::|.....:.:..:|:::..::.:|:.|:..
Worm    68 TKSDDPKAIAKQAPPAMFKVQGCSRLDGDSLSQENAEKPAIVIELENRLVQQRAQRRKIIAN--- 129

  Fly   959 DCIVVPLLRGSLDDAVRQSDPDVPSTSAAMENI-IEVDYSSLPREYTKLKDDSAFKKTH-EMLQK 1021
                           |...|.|:|:..|...:. ::.||||||.|..|..:|:...|.| ..|::
Worm   130 ---------------VTLQDLDIPAKEAGTFSYDVKPDYSSLPDELKKESNDAETVKMHLRTLEE 179

  Fly  1022 DLQSKLD---VLERIQTPNMKALQKLDAVTEKVQSTNEEFENARKKAKRAKAAFERVKNERSSRF 1083
            .:|:..:   .:...:.|:|      ..:..:...|:.....|:.:....:|..|:||..|.:.|
Worm   180 TIQATRNEWVAVNGAEYPDM------SNILIRFHETDSFINIAKLRTTELEAEIEQVKASRRTHF 238

  Fly  1084 VACCQHISDAIDGIYKKLARNEAAQAYIGPDNPEEPY 1120
            ......:|.::..||::::.:..:...:...|.:|||
Worm   239 NQRLAAVSSSVSRIYREISEDPDSTVSLASSNEDEPY 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SMC1	NP_651211.2	Smc	26..1216	CDD:224117	60/297 (20%)
		ABC_SMC1_euk	27..>171	CDD:213242
		SMC_hinge	535..653	CDD:214944
		DUF4700	<697..>810	CDD:292399
		ABC_SMC1_euk	<1130..1232	CDD:213242
C44C10.5	NP_001359562.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1196
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810