Protein Alignment Hsp68 and SSE2

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_009728.1
• Gene: SSE2 / 852467
• SGDID: S000000373
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 644
• Identity: 189/644 - (29%)
• Similarity: 317/644 - (49%)
• Gaps: 71/644 - (11%)

  Fly     5 GIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDAKR 69
            |:|||...|.:.|.:...::::.|:..||:|||.|.|....|.:|::.|.:...|.||:|.:.||
Yeast     6 GLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKR 70

  Fly    70 LIGRRFDDSKIQEDIKHWPFKVIN-DNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYLG 133
            :||.:|.|.:...:.|.:..|::. .|||..:.|||.|....||..::::|.:.|:|.|.:....
Yeast    71 IIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETK 135

  Fly   134 TTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKN-LKG----ERNVL 193
            :::.|..:.||.::::.||....||..|||:|.:||:|:.||||::||:.|| |.|    .|.:.
Yeast   136 SSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIG 200

  Fly   194 IFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRAL 258
            :.|:|..|:..||:...:|.: :|..||.|.|.||.|||..:..|||::||.|||.|:|.||:|.
Yeast   201 LVDIGHSTYTCSIMAFRKGEM-KVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAY 264

  Fly   259 RRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAK 323
            .|:..|||:.|:.||::|.|...::::.:..|..|::||...|||...|.:....|:..||..||
Yeast   265 NRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAK 329

  Fly   324 MDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKD 388
            :..:.|..:.::||:||||.::..:.:.| ||.|:.::|.|||||.|||...||.|  .:..::.
Yeast   330 LTVNDIDFVEIIGGTTRIPVLKKSISDVF-GKPLSSTLNQDEAVAKGAAFICAIHS--PTLRVRP 391

  Fly   389 VLLVDVAPLSLGIETAGGVMTKLIERNSRI---PCKQS----KTFTTYADNQPAVTIQVFEGERA 446
            ....|:.|.|:..     ...|.::...|:   |...|    |..|.:.....::. .|:.....
Yeast   392 FKFEDIDPYSVSY-----TWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMK-AVYTHPSK 450

  Fly   447 LTK-DNNVLGTFDLTGVPPAPRGVPK------IDVTFDLDANGI-------------------LN 485
            |.| .:..:..:..|||.     |||      :.|....|.:|:                   |.
Yeast   451 LPKGTSTTIAKWSFTGVK-----VPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLP 510

  Fly   486 VTAKEQGTGNAKNI--TIKND-------KGRLSQADIDRMLSEAEKYAEEDERHRQRIAARNQLE 541
            ..|.|......|.:  |||.|       ...|:..:::.::.:..:...:|:...:....:|.||
Yeast   511 EDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALE 575

  Fly   542 TYLFGVKEAAENG-GDRISAADKSSIVERCSEAMKWL----DSNTTAEKEEYEYKLKEL 595
            .|::.::...::. .|..|.|:|..:....:....||    |.:|   |.:|..|.:||
Yeast   576 EYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDST---KAKYIAKYEEL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	189/644 (29%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	140/379 (37%)
SSE2	NP_009728.1	HSP70	4..644	CDD:394970	189/644 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810