Protein Alignment Hsp68 and SSB1

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_010052.1
• Gene: SSB1 / 851369
• SGDID: S000002388
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 608
• Identity: 347/608 - (57%)
• Similarity: 449/608 - (73%)
• Gaps: 13/608 - (2%)

  Fly     3 AIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDA 67
            |||||||||||||..:: ..||||||:||||.|||:||||..|||||||||||.|:||:|:||||
Yeast     9 AIGIDLGTTYSCVATYE-SSVEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPRNTVFDA 72

  Fly    68 KRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYL 132
            ||||||||||..:|:|:|.||||||:.:|.|.|.|::....|.|||:|||:||||||||.|||.:
Yeast    73 KRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKI 137

  Fly   133 GTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGL--DKNLKGERNVLIF 195
            |..|:.|||||||||||:|||||||||||:|:|||||||||||||:||||  .|:.| ||:||||
Yeast   138 GKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEK-ERHVLIF 201

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRR 260
            ||||||||||:|.| .|.::.|:||:|:|||||:|||..|:.||..|||:|...|:..:.|||||
Yeast   202 DLGGGTFDVSLLHI-AGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRR 265

  Fly   261 LRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMD 325
            ||||||||||||||.|:.::|:|:|::|.||.|.::|||||:|...||::||||||:.|||||:.
Yeast   266 LRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKIS 330

  Fly   326 KSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSS-EIKDV 389
            ||||.::|||||||||||||.||.:||.||.|..|||||||||||||:|.|||:|..:| |.||:
Yeast   331 KSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDL 395

  Fly   390 LLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVL 454
            ||:||||||||:...|.:...::.||:.:|..:.:||||.||||..|...|::|||...|:|.:|
Yeast   396 LLLDVAPLSLGVGMQGDMFGIVVPRNTTVPTIKRRTFTTCADNQTTVQFPVYQGERVNCKENTLL 460

  Fly   455 GTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSE 519
            |.|||..:|..|.|.|.::..|::||||||.|||.|:.||.:.||||.|..||||..:|::|:::
Yeast   461 GEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQ 525

  Fly   520 AEKYAEEDERHRQRIAARNQLETYLFGVKEAAENG--GDRISAADKSSIVERCSEAMKWLDSNTT 582
            ||::...||...::..||.:||:|:..:::...:.  ..::....||.|....|:|:..|.....
Yeast   526 AEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDALAALQIEDP 590

  Fly   583 AEKEEYEYKLKELEQFCSPIMTK 605
            :..|     |::.|.....::||
Yeast   591 SADE-----LRKAEVGLKRVVTK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	347/608 (57%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	259/377 (69%)
SSB1	NP_010052.1	PTZ00009	6..575	CDD:240227	338/568 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341916
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.640