DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp68 and AT3G09440

DIOPT Version :9

Sequence 1:	NP_524474.1	Gene:	Hsp68 / 42852	FlyBaseID:	FBgn0001230	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001189847.1	Gene:	AT3G09440 / 820102	AraportID:	AT3G09440	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	649	Identity:	427/649 - (65%)
Similarity:	524/649 - (80%)	Gaps:	22/649 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFD 66
            ||||||||||||||||:|:.:||||||||||||||||||||||||||||||||||||||.|:|||
plant     8 PAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPINTVFD 72

  Fly    67 AKRLIGRRFDDSKIQEDIKHWPFKVINDNG-KPKISVEFKGANKCFSPEEISSMVLTKMKETAEA 130
            |||||||||.||.:|.|||.|||.:.:... ||.|.|.:||.:|.||.||||||:|.||:|.|||
plant    73 AKRLIGRRFTDSSVQSDIKLWPFTLKSGPAEKPMIVVNYKGEDKEFSAEEISSMILIKMREIAEA 137

  Fly   131 YLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLK--GERNVL 193
            |||||:|:||:||||||||||||||||||.|||:||:||||||||||:||||||...  ||:|||
plant   138 YLGTTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVL 202

  Fly   194 IFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRAL 258
            ||||||||||||:|||:|| :|||::|||||||||||||||:||||.:|||||.|||:..|||||
plant   203 IFDLGGGTFDVSLLTIEEG-IFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRAL 266

  Fly   259 RRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAK 323
            ||||||.|||||||||:.:.::|||:|::|.|||:.::|||||||..||||..:|||||.|:|||
plant   267 RRLRTACERAKRTLSSTAQTTIEIDSLFDGIDFYAPITRARFEELNIDLFRKCMEPVEKCLRDAK 331

  Fly   324 MDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKD 388
            |||:.|.|:|||||||||||||.||.:||.||.|..|||||||||||||:|||||||:.:.:::|
plant   332 MDKNSIDDVVLVGGSTRIPKVQQLLVDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQD 396

  Fly   389 VLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNV 453
            :||:||.|||||:||||||||.||:||:.||.|:.:.|:||:||||.|.|||:|||||.|||||:
plant   397 LLLLDVTPLSLGLETAGGVMTVLIQRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNNL 461

  Fly   454 LGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLS 518
            ||.|:|:|:||||||||:|.|.||:||||||||:|:::.||....|||.|||||||:.:|::|:.
plant   462 LGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMVQ 526

  Fly   519 EAEKYAEEDERHRQRIAARNQLETYLFGVKEAA--ENGGDRISAADKSSIVERCSEAMKWLDSNT 581
            |||||..|||.|::::.|:|.||.|.:.::...  |..|::::..||..|.:....|::||::|.
plant   527 EAEKYKSEDEEHKKKVDAKNALENYAYNMRNTIRDEKIGEKLAGDDKKKIEDSIEAAIEWLEANQ 591

  Fly   582 TAEKEEYEYKLKELEQFCSPIMTKMHKGGGDGQQAPNFGQQAGGY----------KGPTVEEVD 635
            .||.:|:|.|:||||..|:||:.||::||..|      |..|||.          .||.:||||
plant   592 LAECDEFEDKMKELESICNPIIAKMYQGGEAG------GPAAGGMDEDVPPSAGGAGPKIEEVD 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	425/647 (66%)
Hsp68	NP_524474.1	HSPA1-2_6-8-like_NBD	3..379	CDD:212675	287/378 (76%)
AT3G09440	NP_001189847.1	PTZ00009	5..649	CDD:240227	425/647 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730