Protein Alignment Hsp68 and hspa12a

DIOPT Version :10

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001417784.2
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 670
• Species: Danio rerio
• Alignment Length: 667
• Identity: 138/667 - (20%)
• Similarity: 234/667 - (35%)
• Gaps: 212/667 - (31%)

  Fly     4 IGIDLGTTYS-----------CVGVFQYGKVEIIANDQG--NRTTPSYVAFTDSERL--IGDAAK 53
            :.||.|||.|           |:...:..:    ..|.|  |:.||:.:..|..::.  .|.||:
Zfish    56 VAIDFGTTSSGYAYAFTKEPECIHTMRRWE----GGDPGVSNQKTPTTILLTPDKKFHSFGYAAR 116

  Fly    54 N-QVAMNPKNSVFDAKRLIGRRFDDSKIQEDIKHW----PFKV-INDNGKPKISVEFKGAN-KCF 111
            : ...::|..|                     |.|    .||: ::......|..:...|| |..
Zfish   117 DFYHDLDPTES---------------------KQWLYLEKFKMKLHTTANLSIDTDLHAANGKKV 160

  Fly   112 SPEEISSMVLTKMKETAEAYL----GTTVKDA----VITVPAYFNDSQRQATKDAGAIAGI---- 164
            ...:|.:..|...||.|...|    |....:|    ||||||.:....:|..::|...|.:
Zfish   161 KALDIFAYALAFFKEQALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRE 225

  Fly   165 --NVLRIINEPTAAAL--------------------AYGLDKN---------------------- 185
              :.|.|..||.||::                    .|....|
Zfish   226 NPDQLIIALEPEAASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFL 290

  Fly   186 ------------LKGERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFDN 233
                        .:|:|.|:: |.||||.|:::  :.:.||.|.|:...:|..:  :|.: :|:.
Zfish   291 VENVIGELWSELAEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEK 354

  Fly   234 RLVNHFAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRA 298
            .|...|.::|..::|   ...|.|...|..|.|..||..:......|.|:..:...|:|.|....
Zfish   355 LLCKIFGQDFIDQFK---IKRPAAWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGH 416

  Fly   299 RFE-----------------------ELCGDLFRNTLEPVEKALKDAKMDKSQIHDI---VLVGG 337
            ..|                       :....||:.|::.:.:.|.:. .|:.::.||   .||||
Zfish   417 SVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGG 480

  Fly   338 STRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIE 402
            ....|.:|..:||...|:: .:.|..|..:   ..::.|:|.|...|.||    |..:||:.|:
Zfish   481 FAESPLLQQAVQNMLQGRS-RIIIPHDVGL---TILKGAVLFGLDPSIIK----VRRSPLTYGV- 536

  Fly   403 TAGGVMTKLIER--------------------NSRIPCKQS--------KTFTTYADNQPAVTIQ 439
               ||:.:.:|.                    ::.|...||        :::|....:|..:.|.
Zfish   537 ---GVLNRFVEGKHPPEKMLVKDGMRWCTDVFDTFISADQSVALGETVKRSYTPAKPSQQVIVIH 598

  Fly   440 VFEGERALTKDNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQ-------GTGNAK 497
            |:..|:...       || :|     ..||.|.. :..||.:|..:..|:.:       |....:
Zfish   599 VYCSEKESV-------TF-IT-----DPGVRKCG-SLKLDVSGTESPAARREIQTLMQFGDTEIR 649

  Fly   498 NITIKNDKGRLSQADID 514
            .:.:.....|..:|.||
Zfish   650 AMAVDVATSRTVKASID 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	138/667 (21%)
hspa12a	NP_001417784.2	None