Protein Alignment Hsp68 and HSPA13

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 168/424 - (39%)
• Similarity: 247/424 - (58%)
• Gaps: 55/424 - (12%)

  Fly     4 IGIDLGTTYSCVGVF--QYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFD 66
            |||||||||..||||  ..|||::|.::.|:.:.||.|:|||::..:|..:......||:|:::|
Human    34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYD 98

  Fly    67 AKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCF--SPEEISSMVLTKMKETAE 129
            |||.||:.|...:::.:|..:||||:|.||..:.||.   :|:..  |||.:.|.:|.|:||.||
Human    99 AKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT---SNETITVSPEYVGSRLLLKLKEMAE 160

  Fly   130 AYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLI 194
            ||||..|.:|||:|||.|:..||.:|.:|..:||:.:||:||||||||:||||.|  ....:||:
Human   161 AYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHK--ADVFHVLV 223

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALR 259
            .||||||.|||:|. .:|.:|..|:.:|:..|||:||:.||:.:..::..:.| ..:.|....:.
Human   224 IDLGGGTLDVSLLN-KQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTY-GFVPSRKEEIH 286

  Fly   260 RLRTAAERAKRTLSSSTEASLEI---------------------DALYEGHD------------- 290
            |||.|.|..|..|:....|.|.:                     |.|....|
Human   287 RLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSD 351

  Fly   291 ---------FYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKSQIHDIVLVGGSTRIPKVQN 346
                     |.:::||..|:.|..|||:..|.|:::.||:..::|::|.::||||||||||:::.
Human   352 KKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQ 416

  Fly   347 LLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSG 380
            ::|.|| ||..|.|::||.||..|.||||.|..|
Human   417 VIQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	168/424 (40%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	167/421 (40%)
HSPA13	NP_008879.3	HSPA13-like_NBD	12..463	CDD:212679	168/424 (40%)
		PRK13930	32..442	CDD:237564	162/415 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		3/36 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820