Protein Alignment Hsp68 and hspa8b

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 644
• Identity: 458/644 - (71%)
• Similarity: 545/644 - (84%)
• Gaps: 11/644 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFD 66
            ||:|||||||||||||||:|||||||||||||||||||||||:|||||||||||||:||.|:|||
Zfish     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPTNTVFD 69

  Fly    67 AKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAY 131
            |||||||||||:.:|.|:|||||.|||||.:||:.||:||..|.|.|||:||||||||||.||||
Zfish    70 AKRLIGRRFDDAVVQSDMKHWPFTVINDNLRPKVQVEYKGETKTFYPEEVSSMVLTKMKEIAEAY 134

  Fly   132 LGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||.|:.:|||||||||||||||||||||.|:|:|||||||||||||:||||||.:..||||||||
Zfish   135 LGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|.||..|||||||||:..|.||:|||
Zfish   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDISDNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDK 326
            |||.|||||||||||:||:|||:||||.|||:.::|||||||..||||.||:||||:|:|||:||
Zfish   264 RTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKLDK 328

  Fly   327 SQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLL 391
            ||:||||||||||||||:|.|||:||.||.||.|||||||||||||:|||||.||||..::|:||
Zfish   329 SQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGT 456
            :||.||||||||||||||.||:||:.||.||::|||||.||||.|.|||:|||||:|||||:||.
Zfish   394 LDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVLIQVYEGERAMTKDNNLLGK 458

  Fly   457 FDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAE 521
            |:|||:||||||||:|:||||:|||||:||:|.::.||....|||.|||||||:.||:||:.|||
Zfish   459 FELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAE 523

  Fly   522 KYAEEDERHRQRIAARNQLETYLFGVKEAAENG--GDRISAADKSSIVERCSEAMKWLDSNTTAE 584
            ||..||:..|::::|:|.||:|.|.:|...|:.  ..:||..||..|:.:|:|.:.|||.|.|||
Zfish   524 KYKAEDDVQREKVSAKNGLESYSFNMKSTVEDEKLKGKISEEDKQKIINKCNEVISWLDKNQTAE 588

  Fly   585 KEEYEYKLKELEQFCSPIMTKMHKG-GGDGQQAPNFG-------QQAGGYKGPTVEEVD 635
            |||:|::.||||:.|:||:||:::| ||..:..|..|       ...||..|||:||||
Zfish   589 KEEFEHQQKELEKLCNPIITKLYQGTGGMPEGMPGGGFPGAGGAPGGGGSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	456/642 (71%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	302/375 (81%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	444/608 (73%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	301/374 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.730