Protein Alignment Hsp68 and hspa12a.2

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_003198604.1
• Gene: hspa12a.2 / 559237
• ZFINID: ZDB-GENE-061009-20
• Length: 571
• Species: Danio rerio
• Alignment Length: 606
• Identity: 126/606 - (20%)
• Similarity: 225/606 - (37%)
• Gaps: 151/606 - (24%)

  Fly     4 IGIDLGTTYSCVGV-FQYGKVE---IIAN---DQGNRT--TPSYVAFTDSE--RLIG-DAAKNQV 56
            |.||.||:||...: |:..:.:   :|.|   |.|..|  ||:.:.|.:.|  :..| ||.....
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESILIPNWGVDYGYNTFKTPTCILFDEHETFQKFGYDAMMTYT 72

  Fly    57 AMNPKNSVFDAKRLIGRRFD----DSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEIS 117
            ....|:..  .|..:...|.    |.:|..|:    .....:.|:.|....|..     |...:.
Zfish    73 RSTVKSQA--RKSFLFEHFKMELYDKEIHRDL----MITAKNGGQMKALTVFSE-----SLRYLK 126

  Fly   118 SMVLTKMKE--TAEAYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINV------LRIINEPT 174
            ...|.|:||  |.:.::.:.| ..|:||||.:|.:.:|..::|...||:.:      |....||.
Zfish   127 DHALEKVKENPTGKTFIASDV-TWVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFALEPE 190

  Fly   175 AAALAYGLDKNLKGERNV-----------------LIFDLGGGTFDVSI-LTIDEGSLFEVRSTA 221
            ||::   ..|:|..|..:                 ::.|.||||.|::: ..:::|.|.|:.:.:
Zfish   191 AASI---YCKHLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELNAAS 252

  Fly   222 GDTHLGGEDFDNRLVNHFAEEFKRK-YKKDLRSNPRALRRLRTAAERAKR-----------TLSS 274
            |: .:||:..|.:.::...|.|..| |.|..:..|....:|:.....||.           ||..
Zfish   253 GN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCPVTLQE 316

  Fly   275 STEASLEIDALYEGHDFYSKVSRARFEE------------LCGDLFRNTLEPVEKALKDAKMDKS 327
            ..:....|::.:||      |..|.::|            ...:..:.|.|.:||...:.:::
Zfish   317 LAKKEKAIESYFEG------VEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKITSNPELN-- 373

  Fly   328 QIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPD---------------------EAVAYGA 371
             |..::||||......::..|:..|....:...:.|.                     .|:.||.
Zfish   374 -IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYGI 437

  Fly   372 AIQA---AILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKT--FTTYAD 431
            .|.|   .:|..|||:.:.          |.|...........:.:...:.|.:.:.  |.....
Zfish   438 RIDAPFDKVLHKDKSNYVN----------SEGQTYCDVCFETFVRKGESVNCDEVRQFFFNPSHT 492

  Fly   432 NQPAVTIQVFEGERALTKDNNV----------LGTFDLTGVPPAPRGVP---KIDVTFDLDANGI 483
            ||.:...|.|.     |.:..|          :|.|:: |:|....|:.   |:::.|     |.
Zfish   493 NQTSAIFQFFS-----TNEKQVQFIDEPGVEPVGFFEV-GMPKTDGGLSREIKLEIKF-----GS 546

  Fly   484 LNVTAKEQGTGNAKNITIKND 504
            ..:.|......:.:..::|:|
Zfish   547 TEMKATATDVDSGETTSVKHD 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	126/606 (21%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	101/464 (22%)
hspa12a.2	XP_003198604.1	HSPA12_like_NBD	6..420	CDD:212671	96/436 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900