Protein Alignment Hsp68 and hspa12a.3

DIOPT Version :10

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 613
• Identity: 122/613 - (19%)
• Similarity: 217/613 - (35%)
• Gaps: 169/613 - (27%)

  Fly     4 IGIDLGTTYSCVGV-------------------FQYGKVEIIANDQGNRTTPSYVAFTDSE--RL 47
            |.||.||:||...:                   |.|...:          ||:.:.|.:.|  :.
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESIQIPNWGVNFGYNTFK----------TPTCILFDEHETFQK 62

  Fly    48 IG-DAAKNQVAMNPKNSVFDAKRLIGRRFD----DSKIQEDIKHWPFKVINDNGKPKISVEFKGA 107
            .| ||........||:..  .|..:...|.    |.:|..|:    .....:.|:.|....|..
Zfish    63 FGYDAMMTYTRSTPKSQA--RKSFLFEHFKMELYDKEIHRDL----MITAKNGGQMKALTVFSE- 120

  Fly   108 NKCFSPEEISSMVLTKMKE--TAEAYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINV---- 166
                |...:....|.|:||  |.:.::.:.| ..|:||||.:|.:.:|..::|...||:.:
Zfish   121 ----SLRYLKDHALEKIKENTTGKTFIASDV-TWVLTVPAIWNAAAKQFMREAAIEAGLVIESEP 180

  Fly   167 --LRIINEPTAAALAYGLDKNLKGERNV-----------------LIFDLGGGTFDVSI-LTIDE 211
              |....||.||::   ..|.|..|..:                 ::.|.||||.|::: ..:::
Zfish   181 ERLVFALEPEAASI---YCKQLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVED 242

  Fly   212 GSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRK-YKKDLRSNPRALRRLRTAAERAKR----- 270
            |.|.|:.:.:|: .:||:..|.:.::...|.|..| |.|..:..|....:|:.....||.
Zfish   243 GKLKELNAASGN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLV 306

  Fly   271 ------TLSSSTEASLEIDALYEGHDFYSKVSRARFEE------------LCGDLFRNTLEPVEK 317
                  ||....:....|::.:||      |..|.::|            ...:..:.|.|.:||
Zfish   307 LIQCPVTLQDLAKKEKAIESYFEG------VEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEK 365

  Fly   318 ALKDAKMDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPD------------------ 364
            .:.:.:::   |..::||||......::..|:..|....:...:.|.
Zfish   366 IMSNPELN---IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVK 427

  Fly   365 ---EAVAYGAAIQA---AILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQS 423
               .|:.||..|.|   .:|...|:|.:.          |.|...........:.:...:.|.:.
Zfish   428 SRMSALTYGIRIDAPFDKVLHKGKTSYVN----------SEGQTYCDVCFETFVRKGESVNCDEV 482

  Fly   424 KT--FTTYADNQPAVTIQVFEGERALTKDNNV----------LGTFDLTGVPPAPRGVP---KID 473
            :.  |.....||...|.|.|.     |.:..|          :|.|.: |:|....|:.   |::
Zfish   483 RQFFFNPSDTNQTFATFQFFS-----TNEKQVQFIDEPGVESVGVFQV-GMPKTDGGLSREIKLE 541

  Fly   474 VTFDLDANGILNVTAKEQGTGNAKNITI 501
            :.|   .:..:..||.:..:|...::.:
Zfish   542 IKF---GSTEMKATATDVDSGETTSVKL 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	122/613 (20%)
hspa12a.3	NP_001038346.3	ASKHA_NBD_HSP70_HSPA12	8..420	CDD:466827	93/446 (21%)