Protein Alignment Hsp68 and Hsc70Cb

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 204/704 - (28%)
• Similarity: 338/704 - (48%)
• Gaps: 98/704 - (13%)

  Fly     1 MPAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVF 65
            |..||||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|.||:|.
  Fly     1 MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVG 65

  Fly    66 DAKRLIGRRFDDSKIQEDIKHWPFKV-INDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAE 129
            ..|||:||:|:|..:|.::...|.:| ...:|...|.|.:.|.::.|.||::::|:.||:|||:.
  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130

  Fly   130 AYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGE---RN 191
            |.:.|.|.|.||..|.:|.:::|:|..||..|||:||||::||.||.|||||..||...|   ||
  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRN 195

  Fly   192 VLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPR 256
            |:..|.|..:...|.....:|.|..:.||.  ..:||.|.|..|.::||:||:.:||.:.::|.|
  Fly   196 VIFVDFGHSSLQASACAFTKGKLKMLASTW--DQIGGRDIDLALGDYFAKEFQERYKINAKTNAR 258

  Fly   257 ALRRLRTAAERAKRTLS-SSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALK 320
            |..||.|..|:.|:.:| :||:..|.|:...:..|..|.:.|::.||||..:.:...:..::.|.
  Fly   259 ANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLA 323

  Fly   321 DAKMDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSE 385
            ::|:....||.:.:||||:|||.|:.|::..| .|..:.::|.||||:.|||:|.||:|  .:..
  Fly   324 ESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVF-NKPASTTLNQDEAVSRGAALQCAIMS--PAVR 385

  Fly   386 IKDVLLVDVAPLSLGI--ETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALT 448
            :::..:.|:...::.:  ::.|......||...:..........|.....| ..:.:..|::...
  Fly   386 VREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGP-FNVSIVYGQQVPY 449

  Fly   449 KDNNVLGTFDLTGVPPAPRGVPK-IDVTFDLDANGILNVT--------------------AKEQG 492
            .|..: |.:.:..|.|..||..: :.:...::.|||:.::                    |.|:.
  Fly   450 PDQTI-GVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEEK 513

  Fly   493 TGNAKNIT----------------------------------IKN------DKGR---------- 507
            .|:..|.|                                  :|.      ||.:
  Fly   514 PGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELPL 578

  Fly   508 ------LSQADIDRMLSEAEKYAEEDERHRQRIAARNQLETYLFGVKEAAENGG-DR-ISAADKS 564
                  .|..|:.....:..|....|::..:||.|:|.||.:::.::...:.|. :| :..|::.
  Fly   579 ECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAERE 643

  Fly   565 SIVERCSEAMKWL-DSNTTAEKEEYEYKLKELEQFCSPIMTKMHKGGGDGQQAP 617
            .||.:.::...|| :.....|::.|..:|:.|.|...||..:    ..|.:|.|
  Fly   644 KIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLR----ASDYEQGP 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	203/703 (29%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	151/380 (40%)
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	151/381 (40%)
		HSP70	3..682	CDD:278441	198/685 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740