Protein Alignment Hsp68 and hsc70

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Alignment Length: 645
• Identity: 461/645 - (71%)
• Similarity: 546/645 - (84%)
• Gaps: 13/645 - (2%)

  Fly     2 PAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFD 66
            ||:||||||||||||:||:|||||||||||||||||||||||:||||||||||||||||.|:|||
Zfish     5 PAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSNTVFD 69

  Fly    67 AKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAY 131
            |||||||||||..:|.|:||||||||:|..|||:.||:||..|.|.|||:||||||||||.:|||
Zfish    70 AKRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEISEAY 134

  Fly   132 LGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||.||.:|||||||||||||||||||||.|||:|||||||||||||:||||||.:.|||||||||
Zfish   135 LGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:||||..|||||:|||:..|.||:|||
Zfish   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDK 326
            |||.|||||||||||:||:|||:||||.|||:.::|||||||..||||.|||||||||:||||||
Zfish   264 RTACERAKRTLSSSTQASIEIDSLYEGADFYTSITRARFEELNADLFRGTLEPVEKALRDAKMDK 328

  Fly   327 SQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLL 391
            :||||||||||||||||:|.|||:||.|:.||.|||||||||||||:|||||:||.|..::|:||
Zfish   329 AQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGT 456
            :||.||||||||||||||.||:||:.||.||::|||||:||||.|.|||:|||||:|||||:||.
Zfish   394 LDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGK 458

  Fly   457 FDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAE 521
            |:|||:||||||||:|:||||:||||||||:|.::.||....|||.|||||||:.||:||:.||:
Zfish   459 FELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAD 523

  Fly   522 KYAEEDERHRQRIAARNQLETYLFGVKEAAENG--GDRISAADKSSIVERCSEAMKWLDSNTTAE 584
            :|..|||..|:::.|:|.||:..|.:|...|:.  .|:||..||.:|.::|:|.:.|||.|.|||
Zfish   524 QYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPEDKKTITDKCNEVISWLDKNQTAE 588

  Fly   585 KEEYEYKLKELEQFCSPIMTKMHKGGGDGQQAPNFGQQAGGY---------KGPTVEEVD 635
            |:|||::.||||:.|:||:||:::|.| |......|...|||         .|||:||||
Zfish   589 KDEYEHQQKELEKVCNPIITKLYQGAG-GMPGGMPGGMPGGYPGGQGSGSSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	459/643 (71%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	306/375 (82%)
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	447/607 (74%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	306/375 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H74294
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.730