Protein Alignment Hsp68 and Hspa12b

DIOPT Version :10

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001381945.1
• Gene: Hspa12b / 311427
• RGDID: 1312004
• Length: 685
• Species: Rattus norvegicus
• Alignment Length: 639
• Identity: 142/639 - (22%)
• Similarity: 232/639 - (36%)
• Gaps: 209/639 - (32%)

  Fly    25 IIANDQGNRTTPSYVAF---TDSERLI-------GD-AAKNQ-----VAMNPKNSVFDAKRLIGR 73
            ::|.|.|  ||.|..||   ||.|.:.       || ...:|     :.:.|: .:|.:.....|
  Rat    62 VVAIDFG--TTSSGYAFSFATDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPE-GIFHSFGYTAR 123

  Fly    74 RFDDSKIQEDIKHW----PFKV----IND----------NGKPKISVE-FKGANKCFSPEEISSM 119
            .:......|:.:.|    .||:    ..|          |||..:::| |..|.:.|...
  Rat   124 DYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEH----- 183

  Fly   120 VLTKMKETAEAYLGTTVKDA---VITVPAYFNDSQRQATKDAGAIAGI------NVLRIINEPTA 175
            .|.:::|.:|..|   .|||   |:||||.:....:|..::|..:||:      ..|.|..||.|
  Rat   184 ALQELREQSECML---EKDAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEA 245

  Fly   176 AAL-----------------AYG--------LDKNLKGERNVL---------------------- 193
            |::                 |.|        :|.:.:..|..|
  Rat   246 ASVYCRKLRLHQLMDLSSRTAGGGRLGERRSIDSSFRHAREQLRRSRHSRTFLVESGVGELWSEM 310

  Fly   194 -------IFDLGGGTFDVSILTIDE--GSLFEV-RSTAGDTHLGGED--FDNRLVNHFAEEFKRK 246
                   :.|.||||.|:::..:::  |:|.|: :::.|.....|.|  |:..|...|.|:|..|
  Rat   311 QEGDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIAK 375

  Fly   247 YKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFE---------- 301
            :|   |..|.|...|..|.|..|||.......:|.|...:...|||.|......|
  Rat   376 FK---RQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNF 437

  Fly   302 -------------ELCGDLFRNT----LEPVEKALKDAKMDKSQIHDIVLVGGSTRIPKVQNLLQ 349
                         |...:||:.|    ::.:|..|  ||.:...:..:.||||......:|:.:|
  Rat   438 VKWSSQGMLRMSCEAMNELFQPTVSGIIQHIEMLL--AKPEVQGVKLLFLVGGFAESAVLQHAVQ 500

  Fly   350 NFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMT----- 409
            ...|.:.|.:.:..|..:   ..::.|:|.|    :...|:.|..:||:.|:    ||:.
  Rat   501 EALGNRGLRVVVPHDVGL---TILKGAVLFG----QAPGVVRVRRSPLTYGV----GVLNRFVPG 554

  Fly   410 -----KLIERNSR----------IPCKQS--------KTFTTYADNQPAVTIQVF---------- 441
                 ||:.|:.|          :..:||        :::......|..|.|.::
  Rat   555 HHPPEKLLVRDGRRWCTDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFI 619

  Fly   442 --EGER---ALTKDNNVLGTFDLTGVPPAPR--------GVPKIDVT-FDLDAN 481
              .|.|   ||:.:....|:.:.||..|:.|        |..:|.|| .|:..|
  Rat   620 TDPGVRKCGALSLELEPEGSPENTGTSPSRREIRAAMQFGDTEIKVTAVDVSTN 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	142/639 (22%)
Hspa12b	NP_001381945.1	ASKHA_ATPase-like	61..528	CDD:483947	110/484 (23%)