Protein Alignment Hsp68 and Hspa12a

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_017444569.1
• Gene: Hspa12a / 307997
• RGDID: 1305531
• Length: 691
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 142/655 - (21%)
• Similarity: 228/655 - (34%)
• Gaps: 200/655 - (30%)

  Fly     4 IGIDLGTTYS-----------CVGVFQYGKVEIIANDQG--NRTTPSYVAFTDSERL--IGDAAK 53
            :.||.|||.|           |:.|.:..:    ..|.|  |:.||:.:..|...:.  .|.||
  Rat    75 VAIDFGTTSSGYAYSFTKEPECIHVMRRWE----GGDPGVSNQKTPTTILLTPERKFHSFGYAA- 134

  Fly    54 NQVAMNPKNSVFDAKRLIGRRFDDSKIQEDIKHW----PFKV-INDNGKPKISVEFKGAN-KCFS 112
                               |.|.......:.|.|    .||: ::..|...:..:...|| |...
  Rat   135 -------------------RDFYHDLDPNEAKQWLYLEKFKMKLHTTGDLTMDTDLTAANGKKVK 180

  Fly   113 PEEISSMVLTKMKETAEAYL----GTTVKDA----VITVPAYFNDSQRQATKDAGAIAGI----- 164
            ..||.:..|...||.|...|    |:..:::    ||||||.:....:|..::|...||:
  Rat   181 ALEIFTYALQYFKEQALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAGLASPEN 245

  Fly   165 -NVLRIINEPTAAAL--------------------AYG-------------------------LD 183
             ..|.|..||.||::                    .|.                         |.
  Rat   246 SEQLIIALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQSRTFLV 310

  Fly   184 KNLKGE--------RNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFDNRL 235
            :|:.||        ...::.|.||||.|:::  :.:.||.|.|:....|..:  ||.: :|:..|
  Rat   311 ENVIGEIWSELEEGDKYVVVDSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLL 375

  Fly   236 VNHFAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARF 300
            ...|.|:|..::|   ...|.|...|..|.|..||..:......|.|...:...|:|.|......
  Rat   376 CKIFGEDFIEQFK---IKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSV 437

  Fly   301 E-----------------------ELCGDLFRNTLEPVEKALKD--AKMDKSQIHDIVLVGGSTR 340
            |                       :....||:.|::.:.:.|:|  .|.:.|.:..:.||||...
  Rat   438 EHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDSIIEHLRDLFQKPEVSTVKFLFLVGGFAE 502

  Fly   341 IPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIETAG 405
            .|.:|..:|..||.| ..:.|..|..:   ..::.|:|.|...:.||    |..:||:.|:
  Rat   503 APLLQQAVQAAFGDK-CRIIIPQDVGL---TILKGAVLFGLDPAVIK----VRRSPLTYGV---- 555

  Fly   406 GVMTKLIER--------------------NSRIPCKQS--------KTFTTYADNQPAVTIQVFE 442
            ||:.:.:|.                    :..|...||        :::|....:|..:.|.::.
  Rat   556 GVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKRSYTPAKPSQLVIIINIYS 620

  Fly   443 GER---ALTKDNNV--LGT--FDLTGVP----PAPRGVPKIDVTFDLDANGILNVTAKEQGTGNA 496
            .|.   :...|..|  .||  .||||..    ||.|.:..:....|.:    :..||.:..|..:
  Rat   621 SENDDVSFITDPGVKKCGTLRLDLTGTSGAAVPARREIQTLMQFGDTE----IKATAVDIATSKS 681

  Fly   497 KNITI 501
            ..:.|
  Rat   682 VKVGI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	142/655 (22%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	108/492 (22%)
Hspa12a	XP_017444569.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810