Protein Alignment Hsp68 and Hspa14

DIOPT Version :10

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001004257.1
• Gene: Hspa14 / 307133
• RGDID: 1303296
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 184/509 - (36%)
• Similarity: 295/509 - (57%)
• Gaps: 10/509 - (1%)

  Fly     1 MPAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVF 65
            |.|||:.||.|.:||.|::.|:.:::|||.|:|.||:.||:::.|:::|.|||.....|..::|.
  Rat     1 MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYSEREQVVGLAAKQSRIRNISSTVV 65

  Fly    66 DAKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEA 130
            ..|:::||...|.:.|:.|......||..|||.:..::.....|..|||:::.::.:||||||.:
  Rat    66 KVKQILGRSTADPQAQKYISESKCLVIEKNGKLQYEIDTGEETKLVSPEDVARLIFSKMKETAHS 130

  Fly   131 YLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNL-KGERNVLI 194
            .||:...|.|:|||..|.:.|:.|..:|...||.||||:|:||:||.||||:.::. .|:.|||:
  Rat   131 VLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDCPTGKSNVLV 195

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALR 259
            |.|||.:..:||:.::.| ::.|.||....::||..|.:.|..:.|.||:|.:|.|:|.:.||:.
  Rat   196 FKLGGTSLSLSIMEVNSG-MYRVLSTNTSDNIGGVHFTDSLAQYLASEFQRLFKHDVRGSARAMM 259

  Fly   260 RLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKM 324
            :|..:||.||.:||:...|:..:|:||||.||...|||||||.||..||...:|.|...|:.:..
  Rat   260 KLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAVRALLQQSGF 324

  Fly   325 DKSQIHDIVLVGGSTRIPKVQNLLQNFF-GGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKD 388
            ....|:.:||.|||:|||::|.|:::.| .|..|| ||.|||.:..||||:|.||.|.:|:...|
  Rat   325 TADDINKVVLCGGSSRIPRLQQLIKDLFPAGDLLN-SIPPDEVIPIGAAIEAGILVGKESTSGDD 388

  Fly   389 VLLVDVAP---LSLGIETAG-GVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGE-RALT 448
            .:|::.:.   |..|::.:| ...|.|....:.:|.::..|... ..:..:|.::::|.| :...
  Rat   389 SVLIECSARDILVKGVDESGANRFTVLFPSGTPLPARRQHTLQA-PGSISSVCLELYESEGKNSV 452

  Fly   449 KDNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIK 502
            |:........|..:.....|:..|.....:..:|.|.||..:|.||..:.||::
  Rat   453 KEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQETGKCEAITVE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	183/508 (36%)
Hspa14	NP_001004257.1	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	154/377 (41%)