Protein Alignment Hsp68 and hsp-70

DIOPT Version :10

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 437/644 - (67%)
• Similarity: 526/644 - (81%)
• Gaps: 17/644 - (2%)

  Fly     3 AIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDA 67
            ||||||||||||||::|.|||||:||.:||:||||||||||:|||:|||||:|.|.||:|:||||
 Worm     6 AIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDA 70

  Fly    68 KRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYL 132
            |||||||||:..:|.|||||||.|....|||.:.||.||..:.|:.||||:|||.||||||||.|
 Worm    71 KRLIGRRFDEETVQSDIKHWPFTVKGKQGKPVVEVEVKGEKREFNAEEISAMVLQKMKETAEAVL 135

  Fly   133 GTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |.:|:|||||||||||||||||||||..|||:|.:|||||||||||||||||.:..|:|:|||||
 Worm   136 GHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGITDEKNILIFDL 200

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||:|.|||:|||:||||||||||||||:|::.||..|||||..||:.|||||:||||
 Worm   201 GGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFKRKTGKDISSNPRAIRRLR 265

  Fly   263 TAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKS 327
            ||.|||||||||||||::|:|:|::|.|||||::||||||||.||||.|||||||||:|||.||.
 Worm   266 TACERAKRTLSSSTEATVEVDSLFDGTDFYSKITRARFEELCADLFRKTLEPVEKALRDAKTDKG 330

  Fly   328 QIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLV 392
            :|.::|||||||||||:|.||:.||.||.||.|||||||||:|||:|||:|||.|...|||||||
 Worm   331 RIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAVLSGVKDDTIKDVLLV 395

  Fly   393 DVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTF 457
            ||.|||.||||||||||.||:||:|||.|.||||||||||||.|:|||:|||||:|:||:.||||
 Worm   396 DVVPLSHGIETAGGVMTNLIDRNTRIPAKASKTFTTYADNQPGVSIQVYEGERAMTRDNHRLGTF 460

  Fly   458 DLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEK 522
            :|||:||||||||::|||||:||||||||:|.::.||.:..|||:|:||||||||||||::||::
 Worm   461 ELTGIPPAPRGVPQVDVTFDIDANGILNVSAADKSTGRSNRITIRNEKGRLSQADIDRMVNEAKQ 525

  Fly   523 YAEEDERHRQRIAARNQLETYLFGVKEAAENGGDRISAADKSSIVERCSEAMKWLDSNTTAEKEE 587
            :..||...|.||::|||||.|.|.||:|.|..|..:||.|.....:...:.::|::.||.|:|:|
 Worm   526 FEREDAAQRDRISSRNQLEAYAFQVKQALEEHGSLLSAEDAKRAKDAVEDTLRWMERNTLADKDE 590

  Fly   588 YEYKLKELEQFCSPIMTKMHK-----GGGDGQQAPNFGQQAGGY------KGPTVEEVD 635
            .|.|.|||:..|..|:||||:     |.|.|...      :||:      :||||||||
 Worm   591 IEAKDKELKSICQDILTKMHQQEAQSGSGCGNPG------SGGFHSSNYPQGPTVEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	435/642 (68%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	435/642 (68%)