Protein Alignment Hsp68 and hspa8

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_002937574.2
• Gene: hspa8 / 100496320
• XenbaseID: XB-GENE-955426
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 643
• Identity: 461/643 - (71%)
• Similarity: 548/643 - (85%)
• Gaps: 10/643 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFD 66
            ||:|||||||||||||||:|||||||||||||||||||||||:||||||||||||||||.|:|||
 Frog     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFD 69

  Fly    67 AKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAY 131
            |||||||||:|:.:|.|:|||||.||:|:|:||:.||:|...|.|.|||||||||.||||.||||
 Frog    70 AKRLIGRRFEDAVVQSDMKHWPFNVISDSGRPKVQVEYKAETKSFYPEEISSMVLVKMKEIAEAY 134

  Fly   132 LGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||.||.:|||||||||||||||||||||.|:|:|||||||||||||:||||||.:..||||||||
 Frog   135 LGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:||||..|||||:|||:..|.||:|||
 Frog   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFVAEFKRKHKKDIIDNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDK 326
            |||.|||||||||||:||:|||:||||.|||:.::|||||||..||||.||:||||||:|||:||
 Frog   264 RTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328

  Fly   327 SQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLL 391
            |||||||||||||||||:|.|||:||.||.||.|||||||||||||:||||||||||..::|:||
 Frog   329 SQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGT 456
            :||.||||||||||||||.||:||:.||.||::|||||:||||.|.|||:|||||:|||||:||.
 Frog   394 LDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 458

  Fly   457 FDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAE 521
            |:|||:||||||||:|:||||:||||||||:|.::.||....|||.|||||||:.||:||:.|||
 Frog   459 FELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAE 523

  Fly   522 KYAEEDERHRQRIAARNQLETYLFGVKEAAENG--GDRISAADKSSIVERCSEAMKWLDSNTTAE 584
            ||..|||:.|.:::::|.||:|.|.:|...|:.  ..:||..||..|:::|:|.:.|||.|.|||
 Frog   524 KYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLKGKISDEDKQKILDKCNEVISWLDKNQTAE 588

  Fly   585 KEEYEYKLKELEQFCSPIMTKMHK--GGGDGQQAPNF----GQQAGG-YKGPTVEEVD 635
            |||:|::.||||:.|:||:||:::  ||..|.....|    |..:|| ..|||:||||
 Frog   589 KEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGAGGAPSGGASSGPTIEEVD 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	459/641 (72%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	303/375 (81%)
hspa8	XP_002937574.2	PTZ00009	1..613	CDD:240227	447/608 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930