Protein Alignment Hsp68 and hspa5

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_002941690.1
• Gene: hspa5 / 100492570
• XenbaseID: XB-GENE-480060
• Length: 655
• Species: Xenopus tropicalis
• Alignment Length: 623
• Identity: 374/623 - (60%)
• Similarity: 492/623 - (78%)
• Gaps: 10/623 - (1%)

  Fly     4 IGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFT-DSERLIGDAAKNQVAMNPKNSVFDA 67
            :||||||||||||||:.|:|||||||||||.|||||||| :.|||||||||||:..||:|:||||
 Frog    33 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA 97

  Fly    68 KRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYL 132
            ||||||.::|..:|:|||:.|||||....||.|.|:.....|.|:|||||:|||.||||||||||
 Frog    98 KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYL 162

  Fly   133 GTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..|..||:||||||||:|||||||||.|||:||:||||||||||:||||||. :||:|:|:|||
 Frog   163 GKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKK-EGEKNILVFDL 226

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:||||.| :|||.:|.|||||||||||.|::.||.:.:|:|..||:|.:.||:::||
 Frog   227 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLR 290

  Fly   263 TAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKS 327
            ...|:|||.|||..::.:||::.:||.||...::||:||||..||||:|::||:|.|.||.:.||
 Frog   291 REVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKS 355

  Fly   328 QIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLV 392
            .|.:||||||||||||:|.|::.||.||..:..||||||||||||:||.:||||:  :..|::|:
 Frog   356 DIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQ--DTGDLVLL 418

  Fly   393 DVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTF 457
            ||.||:|||||.||||||||.||:.:|.|:|:.|:|.:||||.|||:|:||||.|||||::||||
 Frog   419 DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTF 483

  Fly   458 DLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEK 522
            ||||:||||||||:|:|||::|.||||.|||:::||||...|||.||:.||:..:|:||:::|||
 Frog   484 DLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEK 548

  Fly   523 YAEEDERHRQRIAARNQLETYLFGVKEA---AENGGDRISAADKSSIVERCSEAMKWLDSNTTAE 584
            :||||::.::||..||:||:|.:.:|..   .|..|.::|:.||.:|.:...|.::||:|:..::
 Frog   549 FAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSD 613

  Fly   585 KEEYEYKLKELEQFCSPIMTKMHKGGGDGQQAPNFGQQ 622
            .||::.|.||||:...||:.|::  ||.|...|...::
 Frog   614 IEEFKAKKKELEEIVQPIVGKLY--GGAGAPPPEGAEE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	374/623 (60%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	246/375 (66%)
hspa5	XP_002941690.1	HSP70	32..636	CDD:365808	370/606 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010