Protein Alignment Hsp68 and hsp70

DIOPT Version :9

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001106370.1
• Gene: hsp70 / 100037899
• XenbaseID: XB-GENE-485626
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 458/638 - (71%)
• Similarity: 547/638 - (85%)
• Gaps: 6/638 - (0%)

  Fly     3 AIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDA 67
            |:|||||||||||||||:|||||||||||||||||||||||:||||||||||||||||:|:||||
 Frog     7 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDA 71

  Fly    68 KRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYL 132
            ||||||:|:|..:|.|:|||||:|::|:||||:.|||||..|.|.|||||||||.||||||||||
 Frog    72 KRLIGRKFNDPVVQSDLKHWPFQVVSDHGKPKVKVEFKGEEKTFFPEEISSMVLIKMKETAEAYL 136

  Fly   133 GTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..|.:|||||||||||||||||||||.|||:|||||||||||||:||||||..:||||||||||
 Frog   137 GHAVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGTRGERNVLIFDL 201

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLR 262
            |||||||||||||:| :|||::|||||||||||||||:||||.||||||:|||:..|.|||||||
 Frog   202 GGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRMVNHFMEEFKRKHKKDISQNKRALRRLR 265

  Fly   263 TAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKS 327
            ||.||||||||||::||:|||:|:||.|||:.::||||||||.||||.|||||||||:|||:|||
 Frog   266 TACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKS 330

  Fly   328 QIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLV 392
            ||.:||||||||||||||.|||:||.|:.||.|||||||||||||:|||||.||||..::|:||:
 Frog   331 QIDEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLL 395

  Fly   393 DVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTF 457
            ||||||||:||||||||.||:||:.||.||::|||||:||||.|.|||||||||:|||||:||.|
 Frog   396 DVAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLGKF 460

  Fly   458 DLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEK 522
            :|:|:||||||||:|:||||:||||||||:|.|:.:|....|||.|||||||:.||::|:.|||:
 Frog   461 ELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKSSGKQNKITITNDKGRLSKEDIEKMVQEAER 525

  Fly   523 YAEEDERHRQRIAARNQLETYLFGVKEAA--ENGGDRISAADKSSIVERCSEAMKWLDSNTTAEK 585
            |..:|:..|::|.|:|.||:|.|.:|...  ||...:||..||..|.|:|::.:.||::|..|||
 Frog   526 YKADDDAQREKIDAKNSLESYAFNLKSMVEDENMKGKISEGDKRIISEKCTQIISWLENNQLAEK 590

  Fly   586 EEYEYKLKELEQFCSPIMTKMHKGGGDGQQ-APNFGQQA--GGYKGPTVEEVD 635
            :||.::.||||:.|.||:||:::|...|.. ..:.|.||  ||..|||:||||
 Frog   591 DEYAFQQKELERVCQPIITKLYQGSMPGSMPGSSCGAQARQGGSSGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	456/636 (72%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	306/375 (82%)
hsp70	NP_001106370.1	PTZ00009	2..643	CDD:240227	456/636 (72%)
		HSPA1-2_6-8-like_NBD	7..382	CDD:212675	306/375 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H74294
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010