Protein Alignment Rox8 and NAM8

DIOPT Version :10

• Sequence 1: NP_732944.2
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_011954.1
• Gene: NAM8 / 856486
• SGDID: S000001128
• Length: 523
• Species: Saccharomyces cerevisiae
• Alignment Length: 419
• Identity: 96/419 - (22%)
• Similarity: 164/419 - (39%)
• Gaps: 100/419 - (23%)

  Fly     9 LYVGNLDSSVSEDLLIALFSTMGPVK--------------SCKIIREPGNDPYAFIEYSNYQAAT 59
            ||:|:||.:..::.:..:::::|...              |...:....|..|.|:::.:...|.
Yeast    56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHAA 120

  Fly    60 TALTAMNKRL--FLEKEIKVNWATSP---GNQPKTDISSHHH--IFVGDLSPEIETETLREAFA- 116
            .||......:  |..|::|:|||||.   .|....::.|.::  ||||||:|.:....|.|.|.
Yeast   121 NALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFELFIN 185

  Fly   117 PFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRT------------- 168
            .:...|:.:||.|..|..||||.||.|....|.:.|:..|.|.::..|:|:.
Yeast   186 RYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHVSGN 250

  Fly   169 ---NWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVY---------NQSSPTNT 221
               |.|:..|......|:...:|........|..|.|  :.|..:.:|         :.:.|.||
Yeast   251 NDYNRSSSSLNNENVDSRFLSKGQSFLSNGNNNMGFK--RNHMSQFIYPVQQQPSLNHFTDPNNT 313

  Fly   222 TVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHGNL 286
            ||:.||. .:::::|.:..:|..||.|..|::...|...|:::|.:.:|..||.......:..:.
Yeast   314 TVFIGGL-SSLVTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIAGMQGFPIANSR 377

  Fly   287 VKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAANAAVAAGAGMPGQMMTQQQIAAATGAAI 351
            |:..||:                           :|...|:...|.:...:..|||        .
Yeast   378 VRLSWGR---------------------------SAKQTALLQQAMLSNSLQVQQQ--------Q 407

  Fly   352 PGQMMTPQQIAAQYPYAYQQMGYWYPPAT 380
            ||               .||..|.|.|::
Yeast   408 PG---------------LQQPNYGYIPSS 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_732944.2	RRM1_TIA1_like	9..80	CDD:409788	17/86 (20%)
		RRM2_TIA1_like	96..170	CDD:409789	28/92 (30%)
		RRM_SF	221..292	CDD:473069	18/70 (26%)
NAM8	NP_011954.1	RRM1_NGR1_NAM8_like	55..144	CDD:410023	18/87 (21%)
		RRM2_SECp43_like	162..241	CDD:409781	28/78 (36%)
		RRM3_NGR1_NAM8_like	312..383	CDD:409782	19/71 (27%)