Protein Alignment Rox8 and RIE1

DIOPT Version :9

• Sequence 1: NP_001262897.1
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_011766.3
• Gene: RIE1 / 853165
• SGDID: S000003482
• Length: 781
• Species: Saccharomyces cerevisiae
• Alignment Length: 630
• Identity: 118/630 - (18%)
• Similarity: 186/630 - (29%)
• Gaps: 257/630 - (40%)

  Fly     6 PKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKII-----REPGNDPYAFIEYSNYQAATTALTAM 65
            |..::||.:..|:|...|..|||..||:.|.|:|     .||..  |.||.|.....|:..:..:
Yeast   194 PGNIFVGGIAKSLSIGELSFLFSKYGPILSMKLIYDKTKGEPNG--YGFISYPLGSQASLCIKEL 256

  Fly    66 NKR------LFL-------EKEIKVNWATSPGNQPKTDISSHHHIFVGDL---SPE-IET----- 108
            |.|      ||:       |:| :::|.....|   .:..:...:|:|:|   :|| :||
Yeast   257 NGRTVNGSTLFINYHVERKERE-RIHWDHVKEN---NNDDNFRCLFIGNLPYHNPEKVETLITPK 317

  Fly   109 -------ETLREAFAPFGEI-------SNCR-----IVRDPHTMKS-----------------KG 137
                   :.|.:.|..|..|       ||.|     ...:..:::|                 ||
Yeast   318 EVIEVIKKELSKKFPDFDIISYYFPKRSNTRSSSSVSFNEEGSVESNKSSNNTNGNAQDEDMLKG 382

  Fly   138 YAFVSFVKKAEAENAIQAMNG-QWIGSRSIRTNWSTRKL-----PPPREPSKGGGQ--------- 187
            |.|:..:...:|..||:..|| .|.|:|.:.......|:     ...|.||.....
Yeast   383 YGFIKLINHEQALAAIETFNGFMWHGNRLVVNKAVQHKVYNNHNSHDRHPSISNHNDMEVLEFAN 447

  Fly   188 ----------------GGGMGGGPGNGSGVK-----------------GSQRHTFEEVYNQ---- 215
                            .....|...:.|.|:                 ..||.:|.|...|
Yeast   448 NPMYDYNNYTYDRYYFNNNKNGNSNDTSNVRYFDSVRSTPVAEKMDLFYPQRESFSEGRGQRVPR 512

  Fly   216 ----------------------SSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVF---- 254
                                  |:...:.:|....|.:...:|| :..:..||.|..|:|.
Yeast   513 FMGNKFDMYQYPSTSYSLPIPMSNQQESNLYVKHIPLSWTDEDL-YDFYKSFGEIISVKVITVGG 576

  Fly   255 ---------------------KDKGFSFIKFVTKEAAAHAIEHTHNSEV-------------HGN 285
                                 ..:|:.|:.|.:...||.||.:|...:|             .||
Yeast   577 SKNKYRQQSNDSSSDNDLPVGSSRGYGFVSFESPLDAAKAILNTDGYQVSKDQVLSVSFAQKRGN 641

  Fly   286 LVKCFWGKENGGDNSANNLNAAA-----AAAAASANVAAVAAANAAVAAGAGMPGQMMTQQQIAA 345
            |.......::..|||:...|...     .|.....|...:.|              :|||.|
Yeast   642 LSSSDDDDQSQTDNSSKFQNFQPHNDYHKAYPTKYNKKFINA--------------LMTQNQ--- 689

  Fly   346 ATGAAIPGQMMTPQQIAAQYPYAYQQMGYWYPPATYPTTQ-------------------MQTQYM 391
                       :.||::.:         .::.|..||.|.                   |...:.
Yeast   690 -----------SQQQVSRE---------NYFIPLQYPNTNTKPVNSYNLISANQNNANWMMPMFP 734

  Fly   392 QQGY------YPYAYPTSAQQAGGVPCI--------QFSAAGYRM 422
            ..|:      .||..|.....|..:|.:        :||:..|.|
Yeast   735 SFGFIPQVPPVPYIIPPQNPAANHIPIMANGSNEEEEFSSGDYSM 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	83/429 (19%)
		RRM1_TIA1_like	9..80	CDD:240798	26/88 (30%)
		RRM2_TIA1_like	96..170	CDD:240799	27/119 (23%)
		RRM3_TIA1_like	221..294	CDD:240800	21/110 (19%)
RIE1	NP_011766.3	PABP-1234	195..757	CDD:130689	111/605 (18%)
		RRM3_CELF1-6	542..634	CDD:409797	18/92 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900