Protein Alignment Rox8 and NGR1

DIOPT Version :9

• Sequence 1: NP_001262897.1
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_009771.3
• Gene: NGR1 / 852513
• SGDID: S000000416
• Length: 672
• Species: Saccharomyces cerevisiae
• Alignment Length: 560
• Identity: 114/560 - (20%)
• Similarity: 192/560 - (34%)
• Gaps: 174/560 - (31%)

  Fly     6 PKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGN-------------------------- 44
            |:||::|:||.|..|..:..::|.:......|:||...|
Yeast    33 PRTLWMGDLDPSFDEATIEEIWSKLDKKVIVKLIRAKKNLLIPCSSTSSSNNNTSEENAENQQSA 97

  Fly    45 ---------------------DP---------YAFIEYSNYQAATTALTAMN------------- 66
                                 ||         |.|:|:...:.|..|| ::|
Yeast    98 SNSTDQLDNSQMININGISFIDPSTTQLHHAGYCFVEFETQKDAKFAL-SLNATPLPNFYSPTTN 161

  Fly    67 -------KRLFLEKEIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAF-APFGEISN 123
                   ||.|     ::|||:....|.....:....:|||||||......|...| ..|..:..
Yeast   162 SQTNPTFKRTF-----RLNWASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKSVKT 221

  Fly   124 CRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRK-------------- 174
            .|::.||.|..|:.:.||.|..:.|...|:..|:|:|...|::|..::|.:
Yeast   222 VRVMTDPLTGSSRCFGFVRFGDEDERRRALIEMSGKWFQGRALRVAYATPRNNMMLQLQEQQQQQ 286

  Fly   175 ----------------------------------LP-------PPREPSKGGGQGGGMGGG-PGN 197
                                              ||       ||...::||.....:... |.|
Yeast   287 QQLQQQHQQLDQEDNNGPLLIKTANNLIQNNSNMLPLNALHNAPPMHLNEGGISNMRVNDSLPSN 351

  Fly   198 GSGVKGSQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFI 262
                          .|| :.||||||:.||..|.. ::..:...|..||||.:||:...|...|:
Yeast   352 --------------TYN-TDPTNTTVFVGGLVPKT-TEFQLRSLFKPFGPILNVRIPNGKNCGFV 400

  Fly   263 KFVTKEAAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAANAAV 327
            ||..:..|..:|:......|.|:.::..||:.:..:...|:....|:...:|..:.|.:||::..
Yeast   401 KFEKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSNAKTNSTIMGASQYMSSNGLRAPSAASSVD 465

  Fly   328 AAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYAYQQMGY--WYPPATYP------TT 384
            .:      :.:.:|.........:..|....||......::.:||.:  :|....|.      .:
Yeast   466 NS------KQILEQYAEDKRRLFLHQQQQQQQQQQQDGNFSMEQMAHNNYYNYNNYDYHRNKNGS 524

  Fly   385 QMQTQYMQQGYYPYAYPTSAQQAGGVPCIQFSAAGYRMVP 424
            ......:|:...||     .|:.|.:...|:|:..|.:.|
Yeast   525 HSDLVNLQRSNVPY-----MQEDGALYPHQYSSPSYSLHP 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	86/400 (22%)
		RRM1_TIA1_like	9..80	CDD:240798	24/146 (16%)
		RRM2_TIA1_like	96..170	CDD:240799	25/74 (34%)
		RRM3_TIA1_like	221..294	CDD:240800	23/72 (32%)
NGR1	NP_009771.3	RRM1_NGR1_NAM8_like	35..180	CDD:410023	27/150 (18%)
		RRM2_NGR1_NAM8_like	191..270	CDD:410025	25/78 (32%)
		RRM	<308..526	CDD:223796	50/239 (21%)
		RRM3_NGR1_NAM8_like	359..430	CDD:409782	22/71 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1842
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.900