DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rox8 and NOP6

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_010068.1	Gene:	NOP6 / 851313	SGDID:	S000002372	Length:	225	Species:	Saccharomyces cerevisiae

Alignment Length:	151	Identity:	37/151 - (24%)
Similarity:	58/151 - (38%)	Gaps:	46/151 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 PPPREPSKGGGQGG------------GMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCGGF 228
            |..:.|:...|..|            |.||...||.  ||::               ..|:.|..
Yeast    38 PEGKRPNSAAGNDGEEPVKKKRKTRRGRGGKGKNGK--KGNR---------------FIVFVGSL 85

  Fly   229 PPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKF-VTKEAAAHAIEHTHNSEV--HGNLVKCF 290
            |.::.:.:|.: ||....|.| :|:..|||.:|::| ..|:..  .|:...:..:  ||.|:|
Yeast    86 PRDITAVELQN-HFKNSSPDQ-IRLRADKGIAFLEFDADKDRT--GIQRRMDIALLQHGTLLK-- 144

  Fly   291 WGKE-------NGGDNSANNL 304
             .|:       .||.||...|
Yeast   145 -EKKINVELTVGGGGNSQERL 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	26/110 (24%)
		RRM1_TIA1_like	9..80	CDD:240798
		RRM2_TIA1_like	96..170	CDD:240799
		RRM3_TIA1_like	221..294	CDD:240800	20/75 (27%)
NOP6	NP_010068.1	NARP1	<1..55	CDD:403685	4/16 (25%)
NOP6	NP_010068.1	RRM_Nop6	78..151	CDD:409834	21/79 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900