DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rox8 and UBP1B

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_564018.1	Gene:	UBP1B / 838309	AraportID:	AT1G17370	Length:	419	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	136/386 - (35%)
Similarity:	195/386 - (50%)	Gaps:	45/386 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDPYAFIEYSNYQAATTALTAMN 66
            |.|..:::||||:...|:|.||..:|:..|||:|||:||:. ...|.|:.|.:.::|..|:.::|
plant    49 DPSTCRSVYVGNIHIQVTEPLLQEVFAGTGPVESCKLIRKE-KSSYGFVHYFDRRSAGLAILSLN 112

  Fly    67 KRLFLEKEIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPH 131
            .|....:.||||||.:.|.  :.|.|||.:|||||||||:....|...|:.:...|:.|::.|..
plant   113 GRHLFGQPIKVNWAYASGQ--REDTSSHFNIFVGDLSPEVTDAMLFTCFSVYPTCSDARVMWDQK 175

  Fly   132 TMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPG 196
            |.:|:|:.||||..:.:|:.||..:.|:|:|||.||.||:|          ||...|........
plant   176 TGRSRGFGFVSFRNQQDAQTAIDEITGKWLGSRQIRCNWAT----------KGATSGEDKQSSDS 230

  Fly   197 NG-----SGVKGSQRHTFEEVYNQSSPTN----TTVYCGGFPPNVISDDLMHKHFVQFGP--IQD 250
            ..     |||....:.|    .|..:|.|    ||||.|...|.|...|| |:||...|.  |::
plant   231 KSVVELTSGVSEDGKDT----TNGEAPENNAQYTTVYVGNLAPEVSQVDL-HRHFHSLGAGVIEE 290

  Fly   251 VRVFKDKGFSFIKFVTKEAAAHAIE--HTHNSEVHGNLVKCFWG-KENGGDNSANNLNAAAAAAA 312
            |||.:||||.|:::.|...||.||:  :|| |.:.|..:||.|| |......::|.|...|.|..
plant   291 VRVQRDKGFGFVRYSTHVEAALAIQMGNTH-SYLSGRQMKCSWGSKPTPAGTASNPLPPPAPAPI 354

  Fly   313 ASANVAAVAA--ANAAVAAGAGM-------PGQMMTQQQIAAATG---AAIPGQMMTPQQI 361
            ...:.:.:.|  ...|::..|||       .||...:|....|||   |...|.....||:
plant   355 PGFSASDLLAYERQLAMSKMAGMNPMMHHPQGQHAFKQAAMGATGSNQAIYDGGYQNAQQL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	104/279 (37%)
		RRM1_TIA1_like	9..80	CDD:240798	28/70 (40%)
		RRM2_TIA1_like	96..170	CDD:240799	31/73 (42%)
		RRM3_TIA1_like	221..294	CDD:240800	35/77 (45%)
UBP1B	NP_564018.1	RRM1_PUB1	56..126	CDD:410026	28/70 (40%)
		RRM2_PUB1	138..217	CDD:410031	35/88 (40%)
		RRM3_PUB1	260..336	CDD:410033	35/77 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I3083
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H87796
Inparanoid	1	1.050	189	1.000	Inparanoid score	I1394
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1066369at2759
OrthoFinder	1	1.000	-	-		FOG0000924
OrthoInspector	1	1.000	-	-		mtm1150
orthoMCL	1	0.900	-	-		OOG6_103013
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X831
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830